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Recombinant human CD28 protein (Active) (ab245796)

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Key features and details

  • Expression system: CHO cells
  • Purity: > 95% SDS-PAGE
  • Active: Yes
  • Tags: Fc tag C-Terminus
  • Suitable for: Functional Studies, SDS-PAGE, HPLC

製品の詳細

  • 製品名

    Recombinant human CD28 protein (Active)
    CD28 タンパク質・ペプチド 製品一覧

  • 生理活性

    Determined by its ability to bind its principal binding partner (B7-1) in a functional ELISA.

  • 精製度

    > 95 % SDS-PAGE.
    >95 % by HPLC analysis.

  • 発現系

    CHO cells

  • アクセッション番号

    P01857

  • タンパク質長

    Protein fragment

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 配列

      NKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVV YGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMY PPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPGGPKSCDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVD GVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPA PIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHE ALHNHYTQKSLSLSPGK

    • 予測される分子量

      41 kDa

    • タグ

      Fc tag C-Terminus

    • 配列の追加情報

      Glycosylated, disulfide-linked homodimer of 734 aa residue whose monomer consists of the 134 aa length extracellular portion of CD28 fused to the 231 aa length Fc portion of human IgG1 by two glycines

特性

Our Abpromise guarantee covers the use of ab245796 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

    HPLC

  • 製品の状態

    Lyophilized
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituent: 0.16% Sodium phosphate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Reconstitute in water to 0.1-1.0 mg/ml.

関連情報

  • 別名

    • CD 28
    • CD28
    • CD28 antigen
    • CD28 molecule
    • CD28_HUMAN
    • MGC138290
    • T cell antigen CD28
    • T cell specific surface glycoprotein
    • T cell specific surface glycoprotein CD28
    • T-cell-specific surface glycoprotein CD28
    • TP44
    see all

  • 機能

    Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.

  • 組織特異性

    Expressed in T-cells and plasma cells, but not in less mature B-cells.

  • 配列類似性

    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • 細胞内局在

    Membrane.
  • Information by UniProt

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab245796 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab245796 は論文での使用が確認できていません。

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