AB158032

Recombinant Human Caspase-2 protein (GST tag N-Terminus)

Name: Recombinant Human Caspase-2 protein (ab158032) | Abcam
Brand: Abcam Limited
SKU: AB158032
Price: 118000 JPY
Availability: InStock

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Recombinant Human Caspase-2 protein (GST tag N-Terminus) is a Human Fragment protein, in the 121 to 220 aa range, expressed in Wheat germ, suitable for ELISA, WB.

別名を表示する

ICH1, NEDD2, CASP2, Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, NEDD-2

1 Images

SDS-PAGE - Recombinant Human Caspase-2 protein (GST tag N-Terminus) (AB158032)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human Caspase-2 protein (GST tag N-Terminus) (AB158032)

ab158032 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Key facts

発現系

Wheat germ

アプリケーション

ELISA, WB

applications

生物活性

アクセッション番号

P42575

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 0.79% Tris HCl, 0.31% Glutathione

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "ELISA": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "WB": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPLCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRS","proteinLength":"Fragment","predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":220,"aminoAcidStart":121,"nature":"Recombinant","expressionSystem":"Wheat germ","accessionNumber":"P42575","tags":[{"tag":"GST","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Dry Ice

短期保存温度

-80°C

長期保存温度

-80°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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製品の性状

製品の状態

Liquid

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一般的な情報

機能

Is a regulator of the cascade of caspases responsible for apoptosis execution (PubMed : 11156409, PubMed : 15073321, PubMed : 8087842). Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (PubMed : 15073321). Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (PubMed : 15073321).. Isoform 1. Acts as a positive regulator of apoptosis.. Isoform 2. Acts as a negative regulator of apoptosis.. Isoform 3. May function as an endogenous apoptosis inhibitor that antagonizes caspase activation and cell death.

配列の類似性

Belongs to the peptidase C14A family.

翻訳後修飾

The mature protease can process its own propeptide, but not that of other caspases.

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information CASP2

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Abcam product promise

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Recombinant Human Caspase-2 protein (GST tag N-Terminus)