AB168069

Recombinant Human C19orf50 protein

Name: Recombinant Human C19orf50 protein (ab168069) | Abcam
Brand: Abcam Limited
SKU: AB168069
Price: 88000 JPY
Availability: InStock

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Recombinant Human C19orf50 protein is a Human Full Length protein, in the 1 to 179 aa range, expressed in Escherichia coli, with >85%, suitable for SDS-PAGE, Mass Spec.

別名を表示する

C19orf50, KXD1, KxDL motif-containing protein 1

1 Images

SDS-PAGE - Recombinant Human C19orf50 protein (AB168069)

SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human C19orf50 protein (AB168069)

3 μg ab168069 on 15% SDS-PAGE

Key facts

精製度

>85% SDS-PAGE

発現系

Escherichia coli

アプリケーション

SDS-PAGE, Mass Spec

applications

生物活性

アクセッション番号

Q9BQD3

アニマルフリー

キャリアフリー

種

Human

バッファー組成

pH: 8 Constituents: 10% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.32% Tris HCl, 0.02% (R*,R*)-1,4-Dimercaptobutan-2,3-diol

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }

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配列情報

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSMDLPDSASRVFCGRILSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMSERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASFLEEEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHVQPGSPAINGRSQTDDEEMTGE","proteinLength":"Full Length","predictedMolecularWeight":"22.1 kDa","actualMolecularWeight":null,"aminoAcidEnd":179,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q9BQD3","tags":[{"tag":"His","terminus":"N-Terminus"}]}]

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出荷温度及び保存条件

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

分注に関する情報

Upon delivery aliquot

保管に関する情報

Avoid freeze / thaw cycle

False

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

C19orf50 also known as Chromosome 19 Open Reading Frame 50 is a protein that has a molecular weight of approximately 17 kDa. The protein expresses in various tissues throughout the body indicating a broad role within cellular activities. Though its exact mechanical function isn’t fully determined it may interact with other proteins due to its expression levels across different systems.

Biological function summary

Proteins associated with C19orf50 engage in cellular development and maintenance. Evidence suggests it acts as part of a protein complex influencing key processes within cells. Its function may intersect with regulatory mechanisms affecting cellular growth and differentiation.

Pathways

Cellular processes involving C19orf50 are linked with cellular signal transduction and metabolic pathways. The protein potentially interacts with key players in these pathways such as mTOR signaling. This connection aids in modulating cellular energy balance with influences observed alongside proteins like AMPK which play a role in energy homeostasis and cellular response to stress.

C19orf50's role involves pathogeneses related to metabolic dysfunction and proliferative disorders. In the context of type 2 diabetes evidence suggests a possible interaction with insulin signaling proteins contributing to impaired glucose metabolism. Additionally research implicates its regulatory influence in some cancers possibly through modulation of pathways involving tumor suppressor proteins like p53.

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製品の性状

製品の状態

Liquid

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一般的な情報

機能

As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed : 25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).

配列の類似性

Belongs to the KXD1 family.

細胞内局在性

Lysosome membrane

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製品プロトコール

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information KXD1

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Abcam product promise

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Recombinant Human C19orf50 protein