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AB276317

Recombinant Human ASAM protein (His tag)

Recombinant Human ASAM protein (His tag)

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Recombinant Human ASAM protein (His tag) is a Human Fragment protein, in the 1 to 233 aa range, expressed in HEK 293 cells, with >97%, < 1 EU/µg endotoxin level, suitable for SDS-PAGE.

別名を表示する

ACAM, ASAM, UNQ318/PRO363, CLMP, CXADR-like membrane protein, Adipocyte adhesion molecule, Coxsackie- and adenovirus receptor-like membrane protein, CAR-like membrane protein

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SDS-PAGE - Recombinant Human ASAM protein (His tag) (AB276317)
  • SDS-PAGE

Supplier Data

SDS-PAGE - Recombinant Human ASAM protein (His tag) (AB276317)

SDS-PAGE analysis of ab276317

Key facts

精製度

>97% SDS-PAGE

エンドトキシンレベル

< 1 EU/µg

発現系

HEK 293 cells

タグ

His tag C-Terminus

アプリケーション

SDS-PAGE

applications

生物活性

No

アクセッション番号

Q9H6B4

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 7.4 Constituents: PBS

storage-buffer

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組合せ製品

Reagents, Controls & Accessories

AB325997

Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color)

SDS-PAGE - Prestained Protein Ladder - Extra broad molecular weight (3-250 kDa, 5-color) (AB325997)

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Secondary Antibodies

AB150113

Goat Anti-Mouse IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (AB150113)

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Proteins & Peptides

AB313361

Recombinant Human WFDC2 Protein (His tag)

Mass Spectrometry - Recombinant Human WFDC2 Protein (His tag) (AB313361)

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Proteins & Peptides

AB276403

Recombinant Human VSIG2 protein (His tag)

SDS-PAGE - Recombinant Human VSIG2 protein (His tag) (AB276403)

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Proteins & Peptides

AB87361

Recombinant Human 14-3-3 zeta protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human 14-3-3 zeta protein (His tag N-Terminus) (AB87361)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"linker":null,"sequence":"MSLLLLLLLVSYYVGTLGTHTEIKRVAEEKVTLPCHHQLGLPEKDTLDIEWLLTDNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVKNSGRYVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQYVQSIGM","proteinLength":"Fragment","predictedMolecularWeight":"25.8 kDa","actualMolecularWeight":null,"aminoAcidEnd":233,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"HEK 293 cells","accessionNumber":"Q9H6B4","tags":[{"tag":"His","terminus":"C-Terminus"}]}]
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出荷温度及び保存条件

製品の状態
Lyophilized
出荷温度
Ambient - Can Ship with Ice
短期保存温度
-20°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The ASAM protein also known as the Adipocyte plasma Membrane Associated Protein (APPL1) is a transmembrane protein with a mass around 34 kDa. It is highly expressed in adipose tissue and endothelial cells but appears across a range of tissues. The ASAM protein plays a role in adhesion processes by facilitating cell-cell interactions and is important in maintaining cellular architecture. It interacts with multiple binding partners suggesting diverse functionality and involvement in cellular signaling pathways.
Biological function summary

The ASAM protein has significant roles in cellular adhesion and signaling. As part of the plasma membrane it modulates interactions between cells and their environment contributing to tissue development and repair. It is not typically known to be part of a larger complex but its ability to bind with other proteins highlights its versatility in cellular regulation. Researchers understand it better in the context of cell structural dynamics and communication processes.

Pathways

Research identifies the ASAM protein as a player in the insulin signaling pathway and the cellular adhesion pathway. In insulin signaling it interacts with proteins such as IGF1R and PI3K connecting it to metabolic regulation and homeostasis. The cellular adhesion pathway finds ASAM working with cadherins and integrins which emphasizes its function in cell communication and structural integrity. Its engagement in these pathways indicates its influence on metabolic processes and cellular response mechanisms.

The ASAM protein shows relevance in conditions like diabetes and obesity. Its involvement in insulin signaling aligns it with metabolic disorders where dysregulation affects glucose uptake and lipid metabolism. Histological studies indicate ASAM interactions with other proteins like FAK and AMPK in the context of these diseases. This connection suggests its potential as a biomarker for metabolic syndromes providing insight into disease development and therapeutic target exploration.
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一般的な情報

機能

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.

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製品プロトコール

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ターゲットの情報

May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.
See full target information CLMP
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