Recombinant Human ASAH1 protein (ab114948)
Key features and details
- Expression system: Wheat germ
- Suitable for: ELISA, SDS-PAGE, WB
製品の詳細
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製品名
Recombinant Human ASAH1 protein
ASAH1 タンパク質・ペプチド 製品一覧 -
発現系
Wheat germ -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
PPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPMLK VIVNSLKNMINTFVPSGKVMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTD -
予測される分子量
37 kDa including tags -
領域
25 to 124
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特性
Our Abpromise guarantee covers the use of ab114948 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
ELISA
SDS-PAGE
Western blot
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製品の状態
Liquid -
備考
Protein concentration is above or equal to 0.05 mg/ml.
Best used within three months from the date of receipt. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.3% Glutathione, 0.79% Tris HCl
関連情報
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別名
- AC
- ACDase
- Acid CDase
see all -
機能
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. -
組織特異性
Broadly expressed with highest expression in heart. -
関連疾患
Defects in ASAH1 are the cause of Farber lipogranulomatosis (FL) [MIM:228000]; also known as Farber disease (FD). This sphingolipid disease is characterized by subcutaneous lipid-loaded nodules, excruciating pain in the joints and extremities, marked accumulation of ceramide in lysosomes, and death by three years of age. -
配列類似性
Belongs to the acid ceramidase family. -
細胞内局在
Lysosome. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human ASAH1 protein (ab114948)12.5% SDS-PAGE showing ab114948 at approximately 36.63kDa.
Stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab114948 は論文での使用が確認できていません。
