Recombinant Human Aromatase protein (ab114260)
Key features and details
- Expression system: Wheat germ
- Purity: >= 80% Purified via GST Tag
- Tags: GST tag N-Terminus
- Suitable for: ELISA, SDS-PAGE, WB
製品の詳細
-
製品名
Recombinant Human Aromatase protein -
精製度
>= 80 % Purified via GST Tag.
Glutathione Sepharose -
発現系
Wheat germ -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
-
生物種
Human -
配列
MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGP GYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKS SSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMK ALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSN TLFLRIPLDGTEIFTLTS -
予測される分子量
50 kDa including tags -
領域
1 to 218 -
タグ
GST tag N-Terminus -
配列の追加情報
Isoform 2 of Aromatase.
-
関連製品
-
Related Products
特性
Our Abpromise guarantee covers the use of ab114260 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
ELISA
SDS-PAGE
Western blot
-
製品の状態
Liquid -
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.3% Glutathione, 0.79% Tris HCl
関連情報
-
別名
- ARO
- ARO1
- Aromatase
see all -
機能
Catalyzes the formation of aromatic C18 estrogens from C19 androgens. -
組織特異性
Brain, placenta and gonads. -
関連疾患
Defects in CYP19A1 are a cause of aromatase excess syndrome (AEXS) [MIM:139300]; also known as familial gynecomastia. AEXS is characterized by an estrogen excess due to an increased aromatase activity.
Defects in CYP19A1 are the cause of aromatase deficiency (AROD) [MIM:107910]. AROD is a rare disease in which fetal androgens are not converted into estrogens due to placental aromatase deficiency. Thus, pregnant women exhibit a hirsutism, which spontaneously resolves after post-partum. At birth, female babies present with pseudohermaphroditism due to virilization of extern genital organs. In adult females, manifestations include delay of puberty, breast hypoplasia and primary amenorrhoea with multicystic ovaries. -
配列類似性
Belongs to the cytochrome P450 family. -
細胞内局在
Membrane. - Information by UniProt
画像
-
SDS-PAGE - Recombinant Human Aromatase protein (ab114260)ab114260 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab114260 は論文での使用が確認できていません。
