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AB109953

Recombinant Human ARL11 protein

Recombinant Human ARL11 protein

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Recombinant Human ARL11 protein is a Human Full Length protein, in the 1 to 196 aa range, expressed in Escherichia coli, with >90%, suitable for SDS-PAGE, Mass Spec.

別名を表示する

ARLTS1, ARL11, ADP-ribosylation factor-like protein 11, ADP-ribosylation factor-like tumor suppressor protein 1

1 Images
SDS-PAGE - Recombinant Human ARL11 protein (AB109953)
  • SDS-PAGE

Unknown

SDS-PAGE - Recombinant Human ARL11 protein (AB109953)

15% SDS-PAGE analysis of ab109953 (3μg)

Key facts

精製度

>90% SDS-PAGE

発現系

Escherichia coli

タグ

His tag N-Terminus

アプリケーション

SDS-PAGE, Mass Spec

applications

生物活性

No

アクセッション番号

Q969Q4

アニマルフリー

No

キャリアフリー

No

種

Human

バッファー組成

pH: 8 Constituents: 30% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.32% Tris HCl, 0.08% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.03% EDTA

storage-buffer

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "SDS-PAGE": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "Mass Spec": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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配列情報

[{"sequence":"MGSSHHHHHHSSGLVPRGSHMGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVLANKQEAPDALPLLKIRNRLSLERFQDHCWELRGCSALTGEGLPEALQSLWSLLKSRSCMCLQARAHGAERGDSKRS","proteinLength":"Full Length","predictedMolecularWeight":"23.6 kDa","actualMolecularWeight":null,"aminoAcidEnd":196,"aminoAcidStart":1,"nature":"Recombinant","expressionSystem":"Escherichia coli","accessionNumber":"Q969Q4","tags":[{"tag":"His","terminus":"N-Terminus"}]}]
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出荷温度及び保存条件

出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
False
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

ARL11 also known as ADP-ribosylation factor-like 11 is a small GTPase protein involved in cellular processes such as vesicle trafficking and signal transduction. This protein has a mass of approximately 20 kilodaltons. ARL11 is expressed in various tissues with notable levels in the pancreas spleen and peripheral blood leukocytes. Researchers frequently study this target due to its role in cellular mechanics and its diverse tissue expression pattern.
Biological function summary

ARL11 regulates cell growth and apoptosis influencing the cellular response to stress. This protein often functions as part of molecular complexes interacting with elements of the cellular machinery to modulate the cell cycle and cellular proliferation. Through these interactions ARL11 can impact the integrity and functionality of cellular processes which positions it as a point of interest in understanding cell regulation and stress responses.

Pathways

ARL11 plays roles in both the apoptosis and signal transduction pathways. It interacts with proteins such as p53 and other members of the Ras superfamily which are involved in controlling cell cycle progression and apoptosis. These pathways highlight ARL11's involvement in maintaining proper cellular function and response to external and internal signals linking it to broader cellular activity networks.

Researchers associate ARL11 with certain types of cancers including pancreatic cancer and lymphomas. Its interaction with proteins like p53 suggests a role in tumor suppression and regulation of cell cycle checkpoints. Changes in ARL11 function or expression may contribute to oncogenic processes suggesting its potential as a target for therapeutic interventions in cancer treatments.
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製品の性状

製品の状態

Liquid

補足情報

ab109953 was purified using conventional chromatography techniques

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一般的な情報

機能

May play a role in apoptosis. May act as a tumor suppressor.

配列の類似性

Belongs to the small GTPase superfamily. Arf family.

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製品プロトコール

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ターゲットの情報

May play a role in apoptosis. May act as a tumor suppressor.
See full target information ARL11
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