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Recombinant Human ACTR8 protein (ab172851)

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Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level: < 1.000 Eu/µg
  • Tags: His tag N-Terminus
  • Suitable for: HPLC, SDS-PAGE

製品の詳細

  • 製品名

    Recombinant Human ACTR8 protein

  • 精製度

    > 95 % SDS-PAGE.
    ab172851 is greater than 95% pure, as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.

  • エンドトキシン・レベル

    < 1.000 Eu/µg

  • 発現系

    Escherichia coli

  • アクセッション番号

    Q9H981-3

  • タンパク質長

    Full length protein

  • Animal free

    No

  • 由来

    Recombinant

    • 生物種

      Human

    • 配列

      MNHKVMILMKMGFSGIVVHQESVCATYGSGLSSTCIVDVGDQKTSVCCVE DGVSHRNTRIFSWNQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPM ALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEHYLLATQSKQEQSAKATA DRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGSAQGDGLMAGNDSEEA LTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDDTKKKMYSSILVVGG GLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGA VLACLDTTQELWIYQREWQ RFGVRMLRERAAFVW

    • 予測される分子量

      38 kDa including tags

    • 領域

      1 to 329

    • タグ

      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab172851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    HPLC

    SDS-PAGE

  • 製品の状態

    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 99% PBS, 0.02% DTT

関連情報

  • 別名

    • Actin-related protein 8
    • Actr8
    • ARP8_HUMAN
    • hArp8
    • INO80 complex subunit N
    see all

  • 機能

    Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
    Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.

  • 配列類似性

    Belongs to the actin family. ARP8 subfamily.

  • 細胞内局在

    Nucleus. Chromosome. Specifically localizes to mitotic chromosomes.
  • Information by UniProt

プロトコール

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

参考文献 (0)

ab172851 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab172851 は論文での使用が確認できていません。

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