Recombinant Human 24p3R protein (ab153343)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
製品の詳細
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製品名
Recombinant Human 24p3R protein -
発現系
Wheat germ -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MASDPIFTLAPPLHCHYGAFPPNASGWEQPPNASGVSVASAALAASAASR VATSTDPSCSGFAPPDFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQV ILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGVGGAAAGS STGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGH FLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIE EAQSVLRILAERNRPHGQMLGEEAQEALQDLENTCPLPATSSFSFASLLN YRNIWKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAAL ACVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQ GNPNRDLNEAAITTFSVLGLFSSQAAAILSTLLAAEVIPTTVRGRGLGLI MALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKL LPEVLRDGELCRRPSLLRQPPPTRCDHVPLLATPNPAL -
領域
1 to 538 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab153343 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
ELISA
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
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別名
- 24p3 receptor
- 24p3R
- BOCT
see all -
機能
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. -
組織特異性
Expressed in brain. -
配列類似性
Belongs to the major facilitator superfamily. Organic cation transporter family. -
細胞内局在
Cell membrane. Vacuole membrane. Upon LCN2-binding, it is internalized. - Information by UniProt
画像
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SDS-PAGE - Recombinant Human 24p3R protein (ab153343)ab153343 on a 12.5% SDS-PAGE stained with Coomassie Blue.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab153343 は論文での使用が確認できていません。
