Recombinant HIV1 tat protein (ab83353)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: Blocking, WB, SDS-PAGE
製品の詳細
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製品名
Recombinant HIV1 tat protein
HIV1 tat タンパク質・ペプチド 製品一覧 -
生理活性
ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum. -
精製度
> 90 % SDS-PAGE. -
発現系
Escherichia coli -
アクセッション番号
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タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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領域
1 to 101
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関連製品
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Matched antibody pairs
特性
Our Abpromise guarantee covers the use of ab83353 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
Western blot
SDS-PAGE
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製品の状態
Lyophilized -
備考
ab83353 reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -80°C.
Constituent: 0.1% Glycerol
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再構成The protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.
関連情報
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別名
- p14
- Protein Tat
- Transactivating regulatory protein
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関連性
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR. -
細胞内局在
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (4)
ab83353 は 4 報の論文で使用されています。
- Alomar FA et al. HIV-Tat Exacerbates the Actions of Atazanavir, Efavirenz, and Ritonavir on Cardiac Ryanodine Receptor (RyR2). Int J Mol Sci 24:N/A (2022). PubMed: 36613717
- Cheng D et al. The nuclear transcription factor, TAF7, is a cytoplasmic regulator of protein synthesis. Sci Adv 7:eabi5751 (2021). PubMed: 34890234
- Zhou F et al. HIV-1 Tat enhances purinergic P2Y4 receptor signaling to mediate inflammatory cytokine production and neuronal damage via PI3K/Akt and ERK MAPK pathways. J Neuroinflammation 16:71 (2019). PubMed: 30947729
- Qu J et al. The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10. BMC Immunol 13:15 (2012). PubMed: 22471703
