Recombinant HIV1 Nef protein (Beta-Galactosidase) (ab49060)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
製品の詳細
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製品名
Recombinant HIV1 Nef protein (Beta-Galactosidase)
HIV1 Nef タンパク質・ペプチド 製品一覧 -
生理活性
Reacts strongly with human HIV positive serum. -
精製度
> 95 % SDS-PAGE. -
発現系
Escherichia coli -
タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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配列の追加情報
Fused with β-galactosidase at the N-terminus.
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特性
Our Abpromise guarantee covers the use of ab49060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
ELISA
Western blot
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製品の状態
Liquid -
備考
Reacts strongly with human HIV positive serum. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.2
Constituents: 0.106% Sodium carbonate, 0.1092% Beta mercaptoethanol, 0.292% EDTA
関連情報
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別名
- C terminal core protein
- F protein
- Nef
see all -
関連性
Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab49060 は論文での使用が確認できていません。