Recombinant HIV1 Nef protein (ab63996)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE
製品の詳細
-
製品名
Recombinant HIV1 Nef protein
HIV1 Nef タンパク質・ペプチド 製品一覧 -
精製度
> 90 % SDS-PAGE.
Highly purified by several steps of chromatography. -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
-
生物種
HIV-1 -
配列
MGGKWSKSSVVGWPTVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAA TNAACAWLEA QEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLE GLIHSQRRQDILDLWIYHTQGY FPDWQNYTPGPGVRYPLTFGWCYKLV PVEPDKVEEANKGENTSLLHPVSLHGMDDPEREV LEWRFDSRLAFHHV ARELHPEYFKNC -
領域
1 to 206
-
関連製品
-
Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab63996 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
アプリケーション
SDS-PAGE
-
製品の状態
Liquid -
備考
ab63996 has been derived from infectious plasmid clone pNL4-3 and belongs to Group B of HIV-1. -
Concentration information loading...
前処理および保存
-
保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 6
Constituents: 0.078% Beta mercaptoethanol, 0.316% Tris HCl, 50% Glycerol (glycerin, glycerine), 0.29% Sodium chloride
関連情報
-
別名
- C terminal core protein
- F protein
- Nef
see all -
関連性
Nef is a early protein that appears to play a role in optimizing the host cell environment for viral replication without causing cell death by apoptosis. Nef enhances virus infectivity and pathogenicity. It down modulates surface MHC I molecules and internalized molecules are sequested to the trans-Golgi network. The number of cell surface CD4 antigen are decreased by interacting with the Src family kinase LCK thereby inducing LCK CD4 dissociation and by increasing clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation.
画像
-
SDS-PAGE - Recombinant HIV1 Nef protein (ab63996)Polyacrylamide gel electrophoresis of ab63996.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab63996 は論文での使用が確認できていません。