Recombinant Hepatitis B Virus Core Antigen protein (ab49013)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE, ELISA, WB
製品の詳細
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製品名
Recombinant Hepatitis B Virus Core Antigen protein
Hepatitis B Virus Core Antigen タンパク質・ペプチド 製品一覧 -
生理活性
Reacts strongly with human HBV positive serum. -
精製度
> 95 % SDS-PAGE.
Purification method is proprietary. -
発現系
Escherichia coli -
アクセッション番号
-
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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配列
MDIDPYKEFG ATVELLSFLP SDFFPSVRDL LDNASALYRE ALESPEHCSP HHTALRQAIL CWGELMTLAT WVGGNLEDPI SRDLVVSYVN TNMGLKFRQL LWFHISCLTF GRETVIEYLV SFGVWIRTPP AYRPPNAPIL STLPETTVVR RRGRSPRRRT PSPRRRRSQS PRRRRSQSRE SQC -
予測される分子量
18 kDa -
領域
1 to 183
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特性
Our Abpromise guarantee covers the use of ab49013 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
ELISA
Western blot
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製品の状態
Liquid -
備考
Reacts strongly with human HBV positive serum. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
pH: 7.20
Constituents: 0.02% PBS, 50% Glycerol (glycerin, glycerine), 0.435% Sodium chloride
関連情報
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別名
- C
- Capsid protein
- core
see all -
関連性
Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection. -
細胞内局在
Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab49013 は 3 報の論文で使用されています。
- Li Y et al. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep 38:110284 (2022). PubMed: 35081341
- Toyama M et al. Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly. Virus Res 271:197677 (2019). PubMed: 31376401
- Bláha BAF et al. Development of a high-throughput microscale cell disruption platform for Pichia pastoris in rapid bioprocess design. Biotechnol Prog 34:130-140 (2018). PubMed: 28884522