Recombinant Cynomolgus monkey PD1 protein (Fc Chimera Active) (ab180060)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Suitable for: SDS-PAGE
製品の詳細
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製品名
Recombinant Cynomolgus monkey PD1 protein (Fc Chimera Active)
PD1 タンパク質・ペプチド 製品一覧 -
精製度
> 95 % SDS-PAGE. -
エンドトキシン・レベル
< 1.000 Eu/µg -
発現系
HEK 293 cells -
アクセッション番号
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タンパク質長
Protein fragment -
Animal free
No -
由来
Recombinant -
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生物種
Cynomolgus monkey -
配列
PGWFLESPDRPWNAPTFSPALLLVTEGDNATFTCSFSNASESFVLNWYRM SPSNQTDKLAAFPEDRSQPGQDCRFRVTRLPNGRDFHMSVVRARRNDSGT YLCGAISLAPKAQIKESLRAELRVTERRAEVPTAHPSPSPRPAGQFQ -
予測される分子量
43 kDa including tags -
領域
21 to 167 -
配列の追加情報
PD1 Fc Chimera, fused with Fc fragment of IgG1 at the C terminus. (ABR15751.1).
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特性
Our Abpromise guarantee covers the use of ab180060 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
pH: 7.4
Constituents: 5% Trehalose, 0.61% Tris, 0.75% Glycine -
再構成Reconstitute with sterile deionized water to a concentration of 500 µg/ml.
関連情報
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別名
- CD279
- CD279 antigen
- hPD 1
see all -
機能
Possible cell death inducer, in association with other factors. -
関連疾患
Genetic variation in PDCD1 is associated with susceptibility to systemic lupus erythematosus type 2 (SLEB2) [MIM:605218]. Systemic lupus erythematosus is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
配列類似性
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
発生段階
Induced at programmed cell death. -
細胞内局在
Membrane. - Information by UniProt
画像
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SDS-PAGE - Recombinant Cynomolgus monkey PD1 protein (Fc Chimera Active) (ab180060)
SDS-PAGE analysis of ab180060 in DTT-reduced (lane 1) and non-reduced (lane 2) conditions. Gel stained overnight with Coomassie Blue. As a result of different glycosylation, DTT-reduced protein migrates as 55-66 kDa and non-reduced protein migrates as 110-140 kDa.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab180060 は論文での使用が確認できていません。
