Human Gastrin peptide (ab42257)
Key features and details
- Purity: > 95% HPLC
- Suitable for: Blocking
製品の詳細
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製品名
Human Gastrin peptide
Gastrin タンパク質・ペプチド 製品一覧 -
精製度
> 95 % HPLC. -
Animal free
No -
由来
Synthetic -
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生物種
Human -
配列
Pyr-GPWLEEEEEAGWMDF -
領域
77 to 92
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関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab42257 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-Gastrin antibody (ab14182)
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
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再構成Resuspend in 60% acetonitrile in 0.01M ammoiumbicarbonate for required concentration (vial content is 0.1 mg).
関連情報
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別名
- Component II
- G14
- G17
see all -
機能
Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. -
配列類似性
Belongs to the gastrin/cholecystokinin family. -
翻訳後修飾
Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only at the most C-terminal dibasic site resulting in the synthesis of gastrin-71.
Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. -
細胞内局在
Secreted. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab42257 は論文での使用が確認できていません。