Human FLASH peptide (ab8455)
Key features and details
- Suitable for: Blocking, WB
製品の詳細
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製品名
Human FLASH peptide -
Animal free
No -
由来
Synthetic -
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生物種
Human -
配列
SERFQQLMKLFEKSKC -
領域
1966 to 1981
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関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab8455 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-FLASH antibody (ab8420)
Western blot
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 0.1% BSA
関連情報
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別名
- AA387232
- C8AP2_HUMAN
- CASP 8 associated protein 2
see all -
機能
Participates in TNF-alpha-induced blockade of glucocorticoid receptor (GR) transactivation at the nuclear receptor coactivator level, upstream and independently of NF-kappa-B. Suppresses both NCOA2- and NCOA3-induced enhancement of GR transactivation. Involved in TNF-alpha-induced activation of NF-kappa-B via a TRAF2-dependent pathway. Acts as a downstream mediator for CASP8-induced activation of NF-kappa-B. Required for the activation of CASP8 in FAS-mediated apoptosis. Required for histone gene transcription and progression through S phase. -
翻訳後修飾
Phosphorylated upon DNA damage, probably by ATM or ATR. -
細胞内局在
Cytoplasm. Nucleus. Localizes to discrete nuclear foci. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab8455 は論文での使用が確認できていません。