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AB204861

Hsp27 peptide

Hsp27 peptide

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(0 Publication)

Hsp27 peptide is a Synthetic peptide. >98% and suitable for FuncS, HPLC.

別名を表示する

HSP27, HSP28, HSPB1, Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, Heat shock protein family B member 1, Stress-responsive protein 27, HSP 27, SRP27

Key facts

精製度

>98% HPLC

タグ

Tag free

アプリケーション

HPLC, FuncS

applications

生物活性

No

アクセッション番号

P04792

アニマルフリー

No

キャリアフリー

No

種

Human

再構成

reconstitute with water at 1mg/mL

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組合せ製品

Reagents, Controls & Accessories

AB234617

Prestained Protein Ladder - Mid-range molecular weight (10 - 180 kDa)

SDS-PAGE - Prestained Protein Ladder - Mid-range molecular weight (10 - 180 kDa) (AB234617)

  • 0
  • 0
Assay Kits

AB263882

Mouse AST ELISA Kit (Aspartate Aminotransferase)

Recombinant|SimpleStep

ELISA - Mouse AST ELISA Kit (Aspartate Aminotransferase) (AB263882)

  • 5
  • 1
Assay Kits

AB65331

L-Lactate Assay Kit (Colorimetric)

Functional Studies - L-Lactate Assay Kit (Colorimetric) (AB65331)

  • 5
  • 2
Primary Antibodies

AB317707

Anti-Hsp27 antibody [RM1148]

BOND RX™ Validated|20ul selling size|RabMAb|KO Validated|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hsp27 antibody [RM1148] (AB317707)

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Multiplex Kits

AB193661

Human HSP Antibody Array - Membrane (9 Targets)

Multiplex Protein Detection - Human HSP Antibody Array - Membrane (9 Targets) (AB193661)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Reactivity", "Dilution Info", "Notes"] }, "values": { "FuncS": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" }, "HPLC": { "reactivity":"TESTED_AND_REACTS", "dilution-info":"", "notes":"<p></p>" } } }
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製品の詳細

ab204861 (Hsp27 peptide) can be utilized as a substrate for the following active protein kinases:

ab85758 (Active human DCAMKL2 protein fragment)
ab60307 (Active MAPKAP Kinase 2 protein fragment)
ab60308 (Active human MAPKAP Kinase 3 full length protein)
ab125743 (Active human PRAK full length protein)

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配列情報

[{"linker":null,"sequence":"RRLNRQLSVA-amide","proteinLength":null,"predictedMolecularWeight":null,"actualMolecularWeight":null,"aminoAcidEnd":85,"aminoAcidStart":80,"nature":"Synthetic","expressionSystem":null,"accessionNumber":"P04792","tags":[]}]
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出荷温度及び保存条件

製品の状態
Lyophilized
出荷温度
Blue Ice
短期保存温度
-20°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle
False
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一般的な情報

機能

Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed : 10383393, PubMed : 20178975). Plays a role in stress resistance and actin organization (PubMed : 19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed : 23728742).

配列の類似性

Belongs to the small heat shock protein (HSP20) family.

翻訳後修飾

Phosphorylated upon exposure to protein kinase C activators and heat shock (PubMed:8325890). Phosphorylation by MAPKAPK2 and MAPKAPK3 in response to stress dissociates HSPB1 from large small heat-shock protein (sHsps) oligomers and impairs its chaperone activity and ability to protect against oxidative stress effectively. Phosphorylation by MAPKAPK5 in response to PKA stimulation induces F-actin rearrangement (PubMed:1332886, PubMed:19166925, PubMed:8093612).

細胞内局在性

Nucleus

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製品プロトコール

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ターゲットの情報

Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PubMed : 10383393, PubMed : 20178975). Plays a role in stress resistance and actin organization (PubMed : 19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed : 23728742).
See full target information HSPB1
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Abcam product promise

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