Active human TRIM5 gamma peptide (ab41839)
Key features and details
- Active: Yes
- Suitable for: Blocking
製品の詳細
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製品名
Active human TRIM5 gamma peptide -
生理活性
Blocking the activity of the TRIM5 gamma antibody (ab17203). -
Animal free
No -
由来
Synthetic -
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生物種
Human
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特性
Our Abpromise guarantee covers the use of ab41839 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- RING finger protein 88
- RNF88
- TRIM5
see all -
機能
Isoform Alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection. Targets retroviral capsid soon after entry into the cell, and prevents reverse transcription of the virus RNA genome. Isoform Alpha trimers may make multiple contacts with the hexameric lattice of CA proteins which constitute the surface of retrovirion core, and somehow inactivate the virus. Restricts efficiently infection by N-MLV, but not HIV-1. May have E3 ubiquitin-protein ligase activity. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger. -
ドメイン
The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme. -
翻訳後修飾
Ubiquitinates itself in a RING finger- and UBE2D2-dependent manner (in vitro). -
細胞内局在
Cytoplasm > P-body. Cytoplasmic bodies. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab41839 は論文での使用が確認できていません。
