Active human TLR5 peptide (ab40018)
Key features and details
- Active: Yes
- Suitable for: Blocking
製品の詳細
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製品名
Active human TLR5 peptide
TLR5 タンパク質・ペプチド 製品一覧 -
生理活性
TLR5 peptide is used for blocking the activity of TLR5 antibody ab37071. -
Animal free
No -
由来
Synthetic -
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生物種
Human
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab40018 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking
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製品の状態
Liquid -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
関連情報
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別名
- FLJ10052
- MGC126430
- MGC126431
see all -
機能
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. -
組織特異性
Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis. -
関連疾患
Systemic lupus erythematosus 1 -
配列類似性
Belongs to the Toll-like receptor family.
Contains 22 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
翻訳後修飾
Phosphorylated at Ser-805 by PKD/PRKD1; phosphorylation induces the production of inflammatory cytokines.
Phosphorylated at Tyr-798 upon flagellin binding; required for signaling. -
細胞内局在
Membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab40018 は論文での使用が確認できていません。