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AB117803

Anti-ZNF687 抗体

Anti-ZNF687 antibody

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(1 Publication)

Rabbit Polyclonal ZNF687 antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ZNF687 aa 100-150.

別名を表示する

KIAA1441, ZNF687, Zinc finger protein 687

1 Images
Immunoprecipitation - Anti-ZNF687 antibody (AB117803)
  • IP

Unknown

Immunoprecipitation - Anti-ZNF687 antibody (AB117803)

Lane 1 : Staining of ZNF687 in HeLa whole cell lysate immunoprecipitated using ab117803 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2 : control IgG. Predicted band size : 130 kDa. Exposure time : 3 minutes

All lanes:

Immunoprecipitation - Anti-ZNF687 antibody (ab117803)

Predicted band size: 129 kDa

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Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

IP

applications

免疫原

Synthetic Peptide within Human ZNF687 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q8N1G0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>" }, "Baboon": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Gorilla": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
ab117803 was affinity purified using an epitope specific to ZNF687 immobilized on solid support.
バッファー組成
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

ZNF687 also known as zinc finger protein 687 is a transcription factor with a known molecular mass of approximately 137 kDa. This protein contains multiple zinc finger motifs that enable its binding to specific DNA sequences regulating the transcription of certain genes. ZNF687 is expressed in various tissues including the brain liver and bone marrow. Its ability to bind DNA is critical for controlling gene expression related to cell proliferation and differentiation.
Biological function summary

ZNF687 functions as a regulatory protein involved in gene expression playing an important role in cellular growth and differentiation. It does not appear to be part of a larger protein complex but acts through binding to specific DNA sequences. The protein helps regulate genes involved in hematopoiesis and neural development suggesting a role in the development and maintenance of these tissues.

Pathways

ZNF687 contributes to gene transcription pathways important for cellular growth and development. It interfaces with signaling pathways such as the MAPK/ERK pathway which is significant for cell proliferation and survival. ZNF687 associates with other transcription factors and its function affects proteins like MYC and FOS which are central to these pathways. By regulating these pathways ZNF687 impacts cellular responses to internal and external stimuli.

ZNF687 is connected to several conditions including osteosarcoma and Paget's disease of bone. Mutations or dysregulation of ZNF687 have been implicated in these diseases potentially through interactions with proteins like SQSTM1 which plays a role in bone remodeling. Research continues to explore ZNF687's contributions to these conditions indicating its relevance in understanding and possibly targeting these diseases.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

May be involved in transcriptional regulation.
See full target information ZNF687
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of translational medicine 23:220 PubMed39985078

2025

SPICE1 promotes osteosarcoma growth by enhancing the deubiquitination of FASN mediated by USP10.

Applications

Unspecified application

Species

Unspecified reactive species

Weilai Tong,Xinsheng Xie,Zhiguo Shu,Jiangbo Nie,Xianhe Yang,Feng Yang,Zhili Liu,Jiaming Liu
View all publications
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