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Anti-ZNF238 抗体 (ab118471)

Submit a review Q&A (1)References (4)
Western blot - Anti-ZNF238 antibody (ab118471)

    Key features and details

    • Rabbit polyclonal to ZNF238
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-ZNF238 antibody

    • 製品の詳細

      Rabbit polyclonal to ZNF238

    • 由来種

      Rabbit

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Human
      交差が予測される動物種: Mouse, Rat

    • 免疫原

      Recombinant fragment, corresponding to amino acids 228-498 of Human ZNF238 (BC036677).

    • ポジティブ･コントロール

      • K562 cell lysate.

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab118471の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    1/500 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).
    特記事項
    WB
    1/500 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).

    ターゲット情報

    • 機能

      Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons (By similarity). Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.

    • 組織特異性

      Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.

    • 配列類似性

      Contains 1 BTB (POZ) domain.
      Contains 4 C2H2-type zinc fingers.

    • 翻訳後修飾

      Phosphorylated upon DNA damage, probably by ATM or ATR.

    • 細胞内局在

      Nucleus. Associates with condensed chromatin.
    • Information by UniProt

    • 参照データベース

      see all

    • 別名

      • C2H2171 antibody
      • 58 kDa repressor protein antibody
      • C2H2 171 antibody
      • RP58 antibody
      • TAZ 1 antibody
      • TAZ-1 antibody
      • TAZ1 antibody
      • Transcriptional repressor RP58 antibody
      • Translin associated zinc finger protein 1 antibody
      • Translin-associated zinc finger protein 1 antibody
      • ZBTB18 antibody
      • Zinc finger and BTB domain containing protein 18 antibody
      • Zinc finger and BTB domain-containing protein 18 antibody
      • Zinc finger protein 238 antibody
      • Zinc finger protein C2H2 171 antibody
      • Zinc finger protein C2H2-171 antibody
      • ZN238_HUMAN antibody
      • ZNF238 antibody
      see all

    画像

    • Western blot - Anti-ZNF238 antibody (ab118471)
      Western blot - Anti-ZNF238 antibody (ab118471)
      Anti-ZNF238 antibody (ab118471) at 1/500 dilution + K562 cell lysate

      Predicted band size: 58 kDa

    参考文献 (4)

    ab118471 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab118471 は 4 報の論文で使用されています。

    • Masilamani AP  et al. Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism. iScience 25:104625 (2022). PubMed: 35800763
    • Liang C  et al. Up-regulated miR-155 is associated with poor prognosis in childhood acute lymphoblastic leukemia and promotes cell proliferation targeting ZNF238. Hematology 26:16-25 (2021). PubMed: 33357126
    • Wang J & Che J CircTP63 promotes hepatocellular carcinoma progression by sponging miR-155-5p and upregulating ZBTB18. Cancer Cell Int 21:156 (2021). PubMed: 33685441
    • Fedele V  et al. Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression. Mol Cancer Res 15:998-1011 (2017). PubMed: 28512252

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    Question

    Would like to try this antibody in ChIP.

    Read More
    Answer

    DISCOUNT CODE: ***
    Expiration date: April 5, 2013
    Value: $337

    This code will give you $337 off your next order before the expiration date. To redeem this offer, please submit an Abreview for ab118471 in ChIP and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active.
    For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

    code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

    Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

    The terms and conditions applicable to this offer can be found here: www.abcam.com/abtrial.

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com