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AB224736

Anti-VPS4B/MIG1 抗体

Anti-VPS4B/MIG1 antibody

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(3 Publications)

Rabbit Polyclonal VPS4B/MIG1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human VPS4B aa 1-150.

別名を表示する

SKD1, VPS42, MIG1, VPS4B, Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-VPS4B/MIG1 antibody (AB224736)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-VPS4B/MIG1 antibody (AB224736)

MCF7 (human breast adenocarcinoma cell line) cells stained for VPS4B/MIG1 (green) using ab224736 (1/100 dilution) in ICC/IF. Secondary : Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VPS4B/MIG1 antibody (AB224736)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VPS4B/MIG1 antibody (AB224736)

Paraffin embedded human small intestine tissue stained for VPS4B/MIG1 with ab224736 (1/100 dilution) in immunohistochemical analysis.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

ICC/IF, IHC-P, WB

applications

免疫原

Recombinant Fragment Protein within Human VPS4B aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

O75351

Reactivity data

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
バッファー組成
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their ATP-dependent disassembly, possibly in combination with membrane fission (PubMed : 18687924). Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).. (Microbial infection) In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
See full target information VPS4B

文献 (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 12:845765 PubMed35936748

2022

Differential Expression and Prognostic Correlation of Immune Related Factors Between Right and Left Side Colorectal Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Hu,Jie Ding,Chengjiang Wu,Hong Gao,Meiling Ge,Qixiang Shao,Yanhong Liu,Qing Ye

Neuropsychiatric disease and treatment 17:41-55 PubMed33442254

2021

MicroRNA-488-3p Regulates Neuronal Cell Death in Cerebral Ischemic Stroke Through Vacuolar Protein Sorting 4B (VPS4B).

Applications

Unspecified application

Species

Unspecified reactive species

Li Zhou,Wanxin Yang,Enping Yao,Haiyan Li,Jihui Wang,Kun Wang,Xiaohua Zhong,Zhongxing Peng,Xuming Huang

The Journal of biological chemistry 295:7941-7957 PubMed32341071

2020

Host ESCRT factors are recruited during chikungunya virus infection and are required for the intracellular viral replication cycle.

Applications

Unspecified application

Species

Unspecified reactive species

Shiho Torii,Yasuko Orba,Michihito Sasaki,Koshiro Tabata,Yuji Wada,Michael Carr,Jody Hobson-Peters,Roy A Hall,Ayato Takada,Takasuke Fukuhara,Yoshiharu Matsuura,William W Hall,Hirofumi Sawa
View all publications

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