violetFluor™ 500 Anti-MHC Class II I Ab + Ad 抗体 [M5/114.15.2]
violetFluor™ 500 Anti-MHC Class II I Ab + Ad antibody [M5/114.15.2]
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Rat Monoclonal HB2Q antibody - conjugated to violetFluor™ 500. Suitable for Flow Cyt and reacts with Mouse samples.
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H2-Ab1
- Flow Cyt
Supplier Data
Flow Cytometry - violetFluor™ 500 Anti-MHC Class II I Ab + Ad antibody [M5/114.15.2] (AB272245)
C57Bl/6 splenocytes were stained with APC Anti-Mouse CD3 and 0.25 ug ab272245 (right panel) or 0.25 ug violetFluor™ 500 Rat IgG2b isotype control (left panel).
Reactivity data
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存温度
長期保存温度
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補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MHC Class II molecules contribute significantly to the adaptive immune response forming part of the peptide-MHC complex. This complex presents processed antigen fragments to T cells. When T cell receptors on CD4+ T cells recognize and bind to these peptide-MHC complexes it triggers signaling cascades that result in T cell activation proliferation and differentiation. The I Ab + Ad refers to specific alleles in different strains of mice models critical for experimental studies in immunology.
Pathways
MHC Class II molecules play an important role in the antigen processing and presentation pathway an essential mechanism for adaptive immune responses. Additionally they participate in the toll-like receptor signaling pathway that helps recognize pathogen-associated molecular patterns. The pathway interactions involve other key proteins like CD4 which is a co-receptor that works alongside T cell receptors to enhance antigen recognition and signaling during immune responses.
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