Anti-VEGFB 抗体 (ab185696)
Key features and details
- Rabbit polyclonal to VEGFB
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-VEGFB antibody
VEGFB 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to VEGFB -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse
交差が予測される動物種: Cow, Human
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免疫原
Recombinant fragment corresponding to Human VEGFB aa 1 to the C-terminus.
Database link: P49765 -
ポジティブ･コントロール
- WB: Mouse heart tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab185696の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 22 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 22 kDa. |
ターゲット情報
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機能
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. -
組織特異性
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. -
配列類似性
Belongs to the PDGF/VEGF growth factor family. -
翻訳後修飾
VEGF-B186 is O-glycosylated. -
細胞内局在
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. - Information by UniProt
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参照データベース
- Entrez Gene: 7423 Human
- Entrez Gene: 22340 Mouse
- Omim: 601398 Human
- SwissProt: P49765 Human
- SwissProt: P49766 Mouse
- Unigene: 78781 Human
- Unigene: 15607 Mouse
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製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- Vascular endothelial growth factor B antibody
- Vascular endothelial growth factor-related factor antibody
- VEGF B antibody
see all
画像
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Western blot - Anti-VEGFB antibody (ab185696)Anti-VEGFB antibody (ab185696) at 1/500 dilution + Mouse heart tissue lysate
Predicted band size: 22 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab185696 は 7 報の論文で使用されています。
- Yen JH et al. Improved Wound Healing by Naringin Associated with MMP and the VEGF Pathway. Molecules 27:N/A (2022). PubMed: 35268795
- Zhang Y et al. Effect of intravitreal conbercept injection on VEGF-A and -B levels in the aqueous and vitreous humor of patients with proliferative diabetic retinopathy. Exp Ther Med 21:332 (2021). PubMed: 33732305
- Zhu X et al. Class A1 scavenger receptor prevents obesity-associated blood pressure elevation through suppressing overproduction of vascular endothelial growth factor B in macrophages. Cardiovasc Res 117:547-560 (2021). PubMed: 32044963
- Wang H et al. Pigment Epithelial-Derived Factor Deficiency Accelerates Atherosclerosis Development via Promoting Endothelial Fatty Acid Uptake in Mice With Hyperlipidemia. J Am Heart Assoc 8:e013028 (2019). PubMed: 31711388
- Rothhammer V et al. Microglial control of astrocytes in response to microbial metabolites. Nature 557:724-728 (2018). PubMed: 29769726
- Lv YX et al. VEGF-A and VEGF-B Coordinate the Arteriogenesis to Repair the Infarcted Heart with Vagus Nerve Stimulation. Cell Physiol Biochem 48:433-449 (2018). PubMed: 30016789
- Lu B et al. Effect of CCL2 siRNA on proliferation and apoptosis in the U251 human glioma cell line. Mol Med Rep 16:3387-3394 (2017). PubMed: 28714025