Anti-VAP1 抗体 (ab187202)
Key features and details
- Rabbit polyclonal to VAP1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
製品の概要
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製品名
Anti-VAP1 antibody
VAP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to VAP1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant fragment corresponding to Human VAP1 aa 1-200.
Database link: Q16853 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187202の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 85 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 85 kDa. |
ターゲット情報
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機能
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. -
組織特異性
Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. -
配列類似性
Belongs to the copper/topaquinone oxidase family. -
翻訳後修飾
Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
N- and O-glycosylated. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 11754 Mouse
- SwissProt: O70423 Mouse
- Unigene: 67281 Mouse
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別名
- Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
- AOC3 antibody
- AOC3_HUMAN antibody
see all
画像
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Western blot - Anti-VAP1 antibody (ab187202)All lanes : Anti-VAP1 antibody (ab187202) at 1/500 dilution
Lane 1 : Mouse kidney tissue extract
Lane 2 : Mouse liver tissue extract
Lane 3 : Mouse heart tissue extract
Predicted band size: 85 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab187202 は 2 報の論文で使用されています。
- Dash PK et al. A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection. Front Cardiovasc Med 8:792180 (2021). PubMed: 34970611
- Zhang Y et al. Hypoxia serves a key function in the upregulated expression of vascular adhesion protein-1 in vitro and in a rat model of hemorrhagic shock. Mol Med Rep 16:1189-1199 (2017). PubMed: 28627649