Anti-USP3 抗体 (ab84702)
Key features and details
- Rabbit polyclonal to USP3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-USP3 antibody
USP3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to USP3 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Chimpanzee, Gorilla
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免疫原
Synthetic peptide corresponding to Human USP3 aa 450-550.
Database link: Q9Y6I4 -
ポジティブ･コントロール
- IHC-P: Human Ovarian Carcinoma, Pancreatic Islet Cell Tumor.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab84702の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/100 - 1/500.
Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
| 特記事項 |
|---|
|
IHC-P
1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
ターゲット情報
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機能
Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. -
組織特異性
Expressed in all tissues examined, with strongest expression in pancreas. -
配列類似性
Belongs to the peptidase C19 family. USP3 subfamily.
Contains 1 UBP-type zinc finger. -
ドメイン
Both protease activity and an intact zinc finger are required for H2A monodeubiquitination. -
細胞内局在
Nucleus. Localizes preferentially with monoubiquitinated H2A to chromatin. - Information by UniProt
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参照データベース
- Entrez Gene: 9960 Human
- GenBank: NM_006537 Human
- Omim: 604728 Human
- SwissProt: Q9Y6I4 Human
- Unigene: 458499 Human
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別名
- Deubiquitinating enzyme 3 antibody
- EC 3.1.2.15 antibody
- SIH003 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP3 antibody (ab84702)ab84702, at 1/100 dilution, staining USP3 in formalin-fixed, paraffin-embedded human ovarian carcinoma by Immunohistochemistry using a Red fluorescent goat anti-rabbit IgG highly cross adsorbed Hilyte PlusTM 555 secondary antibody at a dilution of 1/100.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP3 antibody (ab84702)ab84702, at 1/500 dilution, staining USP3 in formalin-fixed, paraffin-embedded human ovarian carcinoma by Immunohistochemistry using DAB staining. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP3 antibody (ab84702)ab84702, at 1/100 dilution, staining USP3 in formalin-fixed, paraffin-embedded human pancreatic islet cell tumor by Immunohistochemistry using DAB staining.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab84702 は論文での使用が確認できていません。