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AB93721

Anti-Uroplakin III 抗体 [SP73]

Anti-Uroplakin III antibody [SP73]

1

(5 Reviews)

|

(1 Publication)

Rabbit Recombinant Monoclonal Uroplakin III antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication.

別名を表示する

UPK3, UPK3A, Uroplakin-3a, UP3a, Uroplakin III, UPIII

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody [SP73] (AB93721)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody [SP73] (AB93721)

ab93721 at 1/100 dilution staining Uroplakin III in Human bladder carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

関連する標識済み抗体及び組成の異なる製品 (8)

  • Carrier free

    Anti-Uroplakin III antibody [SP73] - BSA and Azide free

  • 660 APC

    APC Anti-Uroplakin III antibody [SP73]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Uroplakin III antibody [SP73]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Uroplakin III antibody [SP73]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Uroplakin III antibody [SP73]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Uroplakin III antibody [SP73]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Uroplakin III antibody [SP73]

  • 578 PE

    PE Anti-Uroplakin III antibody [SP73]

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

SP73

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

エピトープ

C-terminus.

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代替製品

Primary Antibodies

AB187299

Anti-Uroplakin III antibody - C-terminal

Western blot - Anti-Uroplakin III antibody - C-terminal (AB187299)

  • 0
  • 0
Primary Antibodies

AB78196

Anti-Uroplakin III antibody [SFI-1]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody [SFI-1] (AB78196)

  • 4
  • 8
Primary Antibodies

AB231576

Anti-Uroplakin III antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody (AB231576)

  • 5
  • 1
Primary Antibodies

AB187646

Anti-Uroplakin III antibody [EPR14420]

RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody [EPR14420] (AB187646)

  • 0
  • 0
Primary Antibodies

AB239006

Anti-Uroplakin III antibody [EPR14420] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Uroplakin III antibody [EPR14420] - BSA and Azide free (AB239006)

  • 0
  • 0
Primary Antibodies

AB82173

Anti-Uroplakin III antibody

Western blot - Anti-Uroplakin III antibody (AB82173)

  • 0
  • 0
Primary Antibodies

AB150409

Anti-Uroplakin III antibody [EPR3612(2)]

RabMAb|Recombinant

Western blot - Anti-Uroplakin III antibody [EPR3612(2)] (AB150409)

  • 0
  • 1

組合せ製品

Primary Antibodies

AB133616

Anti-CD4 antibody [EPR6855]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD4 antibody [EPR6855] (AB133616)

  • 5
  • 20
Primary Antibodies

AB16662

Anti-ErbB2 / HER2 antibody [SP3]

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ErbB2 / HER2 antibody [SP3] (AB16662)

  • 5
  • 2
Primary Antibodies

AB237709

Anti-CD8 alpha antibody [CAL66]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD8 alpha antibody [CAL66] (AB237709)

  • 5
  • 2
Primary Antibodies

AB16663

Anti-Cyclin D1 antibody [SP4]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|KO Validated|Lab Essentials

Western blot - Anti-Cyclin D1 antibody [SP4] (AB16663)

  • 4
  • 23
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }
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製品の詳細

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A/G
精製に関する特記事項
Purified from TCS by protein A/G.
バッファー組成
pH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
出荷温度
Conditional Ambient
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Uroplakin III also known as UPK3 or UPIII is a transmembrane protein with a molecular weight of around 47 kDa. It is specifically expressed in the urothelium which lines the urinary tract including the bladder ureter and renal pelvis. Uroplakin III plays a structural role by contributing to the formation of the asymmetric unit membrane important for the stability and impermeability of the urothelial barrier.
Biological function summary

Uroplakin III takes part in the formation of the uroplakin complex which includes UPIa UPIb and UPII. It interacts with these proteins to form the urothelial plaques that are essential in maintaining the integrity of the urothelial surface. These plaques prevent urine from permeating back into the underlying tissues ensuring proper urinary function. Uroplakin III also participates in signal transduction mechanisms that may regulate cell proliferation within the urothelial lining.

Pathways

Uroplakin III works within the context of membrane assembly and bladder epithelium differentiation. It interacts with proteins like other uroplakins and cytoskeletal components to mediate the formation of apical urothelial plaques. The protein contributes to signaling pathways that involve cellular differentiation and proliferation ensuring the proper function and renewal of urothelial tissue.

Uroplakin III shows significant relevance in the context of bladder carcinoma and interstitial cystitis. Bladder carcinoma often exhibits altered expression of Uroplakin III suggesting its potential role as a diagnostic marker. In interstitial cystitis changes in Uroplakin III distribution might contribute to the compromised barrier function. Its altered interaction with proteins like uroplakin II can emphasize the link between these structural changes and disease progression.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).
See full target information UPK3A
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 30: PubMed38785151

2024

Oroxylin A inhibits inflammatory cytokines in periodontitis via HO‑1.

Applications

Unspecified application

Species

Unspecified reactive species

Ting Wang,Zhao-Bo Wang,Chun-Miao Jiang,Yang Zhao,Li Tang,Xi-Mei Xiao,Jing Fu
View all publications
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