Anti-Uroplakin III 抗体 - C-terminal (ab187299)
Key features and details
- Rabbit polyclonal to Uroplakin III - C-terminal
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Uroplakin III antibody - C-terminal
Uroplakin III 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Uroplakin III - C-terminal -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Cow
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免疫原
Synthetic peptide corresponding to Human Uroplakin III aa 250 to the C-terminus (C terminal).
Database link: O75631 -
ポジティブ･コントロール
- HEK293 cell lysate; Human bladder carcinoma tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187299の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 31 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 31 kDa. |
ターゲット情報
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機能
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. -
組織特異性
Expressed in ureter. -
関連疾患
Defects in UPK3A are a cause of renal adysplasia (RADYS) [MIM:191830]; also known as renal agenesis or renal aplasia. Renal agenesis refers to the absence of one (unilateral) or both (bilateral) kidneys at birth. Bilateral renal agenesis belongs to a group of perinatally lethal renal diseases, including severe bilateral renal dysplasia, unilateral renal agenesis with contralateral dysplasia and severe obstructive uropathy. -
配列類似性
Belongs to the uroplakin-3 family. -
細胞内局在
Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER). - Information by UniProt
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参照データベース
- Entrez Gene: 100336102 Cow
- Entrez Gene: 7380 Human
- Entrez Gene: 22270 Mouse
- Omim: 611559 Human
- SwissProt: P38574 Cow
- SwissProt: O75631 Human
- SwissProt: Q9JKX8 Mouse
- Unigene: 632787 Human
see all -
別名
- MGC119178 antibody
- OTTHUMP00000028951 antibody
- UP III antibody
see all
画像
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Western blot - Anti-Uroplakin III antibody - C-terminal (ab187299)All lanes : Anti-Uroplakin III antibody - C-terminal (ab187299) at 1 µg/ml
Lane 1 : HEK293 cell lysate
Lane 2 : HEK293 cell lysate with immunizing peptide
Predicted band size: 31 kDa
データシートおよび資料
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Datasheet download
参考文献 (2)
ab187299 は 2 報の論文で使用されています。
- Tang X et al. Construction of lncRNA- and circRNA-associated ceRNA networks in the prostatic urethra of rats after simulating transurethral laser prostatectomy (TULP). Mol Cell Biochem 479:1363-1377 (2024). PubMed: 37410211
- Li X et al. Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder. EBioMedicine 50:23-33 (2019). PubMed: 31757778
