Anti-URG11 抗体 (ab184772)
Key features and details
- Rabbit polyclonal to URG11
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-URG11 antibody -
製品の詳細
Rabbit polyclonal to URG11 -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human URG11 aa 400-550.
Database link: Q96DN2 -
ポジティブ･コントロール
- Human liver tissue; U-2 OS cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab184772の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 1 - 4 µg/ml.
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| IHC-P |
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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ICC/IF
Use a concentration of 1 - 4 µg/ml. |
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IHC-P
1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma. -
組織特異性
Expressed in liver. -
配列類似性
Contains 4 EGF-like domains.
Contains 6 VWFC domains. -
細胞内局在
Secreted. According to PubMed:16496348 is localized in the cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 220001 Human
- Omim: 611115 Human
- SwissProt: Q96DN2 Human
- Unigene: 60640 Human
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別名
- HBV X protein up-regulated gene 11 protein antibody
- HBxAg up-regulated gene 11 protein antibody
- von Willebrand factor C and EGF domain-containing protein antibody
see all
画像
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Immunocytochemistry/ Immunofluorescence - Anti-URG11 antibody (ab184772)
Immunofluorescent analysis of PFA fixed U-2 OS cells labeling URG11 with ab184772 at 4 µg/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-URG11 antibody (ab184772)Immunohistochemical analysis of paraffin embedded Human liver tissue labeling URG11 with ab184772 at 1/1000.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab184772 は 2 報の論文で使用されています。
- Zhao T et al. VWCE modulates amino acid-dependent mTOR signaling and coordinates with KICSTOR to recruit GATOR1 to the lysosomes. Nat Commun 14:8464 (2023). PubMed: 38123554
- Mendaza S et al. ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer. Int J Mol Sci 21:N/A (2020). PubMed: 32019179