Anti-UPP2 抗体 (ab153861)
Key features and details
- Rabbit polyclonal to UPP2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-UPP2 antibody -
製品の詳細
Rabbit polyclonal to UPP2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow
-
免疫原
Recombinant fragment, corresponding to a region within amino acids 1-217 of Human UPP2.
-
ポジティブ･コントロール
- 293T, A431, HeLa and HepG2 cell lysates.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153861の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 36 kDa.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 36 kDa. |
ターゲット情報
-
機能
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates. -
組織特異性
Predominantly expressed in kidney. -
パスウェイ
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1. -
配列類似性
Belongs to the PNP/UDP phosphorylase family. - Information by UniProt
-
参照データベース
- Entrez Gene: 534937 Cow
- Entrez Gene: 151531 Human
- Entrez Gene: 76654 Mouse
- Entrez Gene: 295620 Rat
- SwissProt: O95045 Human
- SwissProt: Q8CGR7 Mouse
- Unigene: 128427 Human
- Unigene: 200370 Mouse
see all -
別名
- Liver specific uridine phosphorylase antibody
- UDRPASE2 antibody
- UP2 antibody
see all
画像
-
Western blot - Anti-UPP2 antibody (ab153861)All lanes : Anti-UPP2 antibody (ab153861) at 1/3000 dilution
Lane 1 : 293T whole cell lysate
Lane 2 : A431 whole cell lysate
Lane 3 : HeLa whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 36 kDa
10% SDS PAGE
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab153861 は 1 報の論文で使用されています。
- Skinner OS et al. Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions. Nat Metab 5:765-776 (2023). PubMed: 37198474