Anti-UGT2B15 抗体 [EPR10615(B)] (ab154864)
![Western blot - Anti-UGT2B15 antibody [EPR10615(B)] (ab154864)](https://www.abcam.co.jp/ps/products/154/ab154864/Images/ab154864-161496-anti-ugt2b15-antibody-epr10615b-western-blot.jpg "Western blot - Anti-UGT2B15 antibody [EPR10615(B)] (ab154864)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR10615(B)] to UGT2B15
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-UGT2B15 antibody [EPR10615(B)]
UGT2B15 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR10615(B)] to UGT2B15 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- LnCaP cell lysate
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPR10615(B) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab154864の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 61 kDa.
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| 特記事項 |
|---|
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WB
1/1000 - 1/10000. Predicted molecular weight: 61 kDa. |
追加情報
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
ターゲット情報
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機能
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites. It also catalyzes the glucuronidation of endogenous estrogens and androgens. -
組織特異性
Expressed in many tissues. Present in liver, prostate and testis. -
配列類似性
Belongs to the UDP-glycosyltransferase family. -
細胞内局在
Microsome membrane. Endoplasmic reticulum membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 7366 Human
- Omim: 600069 Human
- SwissProt: P54855 Human
- Unigene: 150207 Human
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別名
- EC 2.4.1.17 antibody
- HLUG4 antibody
- UDB15_HUMAN antibody
see all
画像
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Western blot - Anti-UGT2B15 antibody [EPR10615(B)] (ab154864)Anti-UGT2B15 antibody [EPR10615(B)] (ab154864) at 1/1000 dilution + LnCap cell lysate at 10 µg
Predicted band size: 61 kDa -
![Anti-UGT2B15 antibody [EPR10615(B)] (ab154864)](https://www.abcam.co.jp/ps/products/154/ab154864/Images/ab154864-2-benefits-of-recombinant-antibodies.png)
Anti-UGT2B15 antibody [EPR10615(B)] (ab154864)
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab154864 は 2 報の論文で使用されています。
- Chen X et al. Bioinformatic analysis suggests that UGT2B15 activates the Hippo-YAP signaling pathway leading to the pathogenesis of gastric cancer. Oncol Rep 40:1855-1862 (2018). PubMed: 30066917
- Shukla S et al. Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance. Cancer Cell 32:792-806.e7 (2017). PubMed: 29153843