Anti-TXNRD1 抗体 [EPR10204(B)] (ab151716)
![Western blot - Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)](https://www.abcam.co.jp/ps/products/151/ab151716/Images/TXNRD1-Primary-antibodies-ab151716-1.jpg "Western blot - Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR10204(B)] to TXNRD1
- Suitable for: WB, IHC-P
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-TXNRD1 antibody [EPR10204(B)]
TXNRD1 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR10204(B)] to TXNRD1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details
適用なし: Flow Cyt,ICC/IF or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Jurkat, HeLa and A549 cell lysates; Human testis tissue.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20ºC. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 0.05% BSA, 59% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR10204(B) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab151716の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 71 kDa.
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| IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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WB
1/1000 - 1/10000. Predicted molecular weight: 71 kDa. |
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IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
追加情報
Is unsuitable for Flow Cyt,ICC/IF or IP.
ターゲット情報
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機能
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. -
組織特異性
Isoform 1 is expressed predominantly in Leydig cells (at protein level). Also expressed in ovary, spleen, heart, liver, kidney and pancreas and in a number of cancer cell lines. Isoform 4 is widely expressed with highest levels in kidney, testis, uterus, ovary, prostate, placenta and fetal liver. -
配列類似性
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Contains 1 glutaredoxin domain. -
ドメイン
The N-terminal glutaredoxin domain found in isoform 1 does not contain the C-P-Y-C redox-active motif normally found in glutaredoxins and has been found to be inactive in classical glutaredoxin assays. -
翻訳後修飾
The N-terminus of isoform 5 is blocked.
ISGylated. -
細胞内局在
Cytoplasm and Cytoplasm. Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 7296 Human
- Omim: 601112 Human
- SwissProt: Q16881 Human
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別名
- cytoplasmic antibody
- Gene associated with retinoic and IFN-induced mortality 12 protein antibody
- Gene associated with retinoic and interferon-induced mortality 12 protein antibody
see all
画像
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Western blot - Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)All lanes : Anti-TXNRD1 antibody [EPR10204(B)] (ab151716) at 1/1000 dilution
Lane 1 : Jurkat cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : A549 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 71 kDa -
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)](https://www.abcam.co.jp/ps/products/151/ab151716/Images/TXNRD1-Primary-antibodies-ab151716-2.jpg)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)Immunohistochemical analysis of Paraffin-embedded Human testis tissue labeling TXNRD1 with ab151716 at 1/50 dilution.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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![Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)](https://www.abcam.co.jp/ps/products/151/ab151716/Images/ab151716-3-benefits-of-recombinant-antibodies.png)
Anti-TXNRD1 antibody [EPR10204(B)] (ab151716)
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab151716 は論文での使用が確認できていません。