Anti-TTK/Mps1 抗体 (ab187520)
Key features and details
- Rabbit polyclonal to TTK/Mps1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-TTK/Mps1 antibody
TTK/Mps1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TTK/Mps1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment corresponding to Human TTK/Mps1 aa 517-856 (C terminal). C-terminal 340AA
Database link: P33981 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187520の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 97 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 97 kDa. |
ターゲット情報
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機能
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. -
組織特異性
Present in rapidly proliferating cell lines. -
配列類似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 protein kinase domain. - Information by UniProt
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参照データベース
- Entrez Gene: 7272 Human
- Entrez Gene: 22137 Mouse
- Omim: 604092 Human
- SwissProt: P33981 Human
- SwissProt: P35761 Mouse
- Unigene: 169840 Human
- Unigene: 1904 Mouse
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別名
- cancer/testis antigen 96 antibody
- CT96 antibody
- Dual specificity protein kinase TTK antibody
see all
画像
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Western blot - Anti-TTK/Mps1 antibody (ab187520)All lanes : Anti-TTK/Mps1 antibody (ab187520) at 1/1000 dilution
Lane 1 : U-251MG cell lysate
Lane 2 : Mouse testis tissue lysate
Lane 3 : Mouse spleen tissue lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : HRP Goat Anti-Rabbit IgG
Predicted band size: 97 kDaBlocking buffer: 3% nonfat dry milk in TBST.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab187520 は 1 報の論文で使用されています。
- Chen F et al. Protein kinase TTK promotes proliferation and migration and mediates epithelial-mesenchymal transition in human bladder cancer cells. Int J Clin Exp Pathol 11:4854-4861 (2018). PubMed: 31949560