Anti-TTC11/FIS1 抗体 (ab71498)
Key features and details
- Rabbit polyclonal to TTC11/FIS1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-TTC11/FIS1 antibody
TTC11/FIS1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TTC11/FIS1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- Jurkat cell lysates
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特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 3491R Fis1 Polyclonal Antibody.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.5% BSA, 30% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab71498の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 17 kDa).
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 17 kDa). |
ターゲット情報
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機能
Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. -
配列類似性
Belongs to the FIS1 family.
Contains 1 TPR repeat. -
ドメイン
The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L. -
翻訳後修飾
Ubiquitinated by MARCH5. -
細胞内局在
Mitochondrion outer membrane. Peroxisome membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 51024 Human
- Entrez Gene: 66437 Mouse
- Entrez Gene: 288584 Rat
- Omim: 609003 Human
- SwissProt: Q9Y3D6 Human
- SwissProt: Q9CQ92 Mouse
- SwissProt: P84817 Rat
- Unigene: 423968 Human
see all -
別名
- 2010003O14Rik antibody
- CGI 135 antibody
- CGI135 antibody
see all
画像
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Western blot - Anti-TTC11/FIS1 antibody (ab71498)All lanes : Anti-TTC11/FIS1 antibody (ab71498) at 1 µg/ml
All lanes : Jurkat cell lysates
Predicted band size: 17 kDa
Observed band size: 17 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (76)
ab71498 は 76 報の論文で使用されています。
- Choi SG et al. PINK1 siRNA-loaded poly(lactic-co-glycolic acid) nanoparticles provide neuroprotection in a mouse model of photothrombosis-induced ischemic stroke. Glia 71:1294-1310 (2023). PubMed: 36655313
- Suh J et al. Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab 35:345-360.e7 (2023). PubMed: 36754021
- Huang Q et al. Ginsenoside compound K protects against cerebral ischemia/reperfusion injury via Mul1/Mfn2-mediated mitochondrial dynamics and bioenergy. J Ginseng Res 47:408-419 (2023). PubMed: 37252276
- Cadile F et al. Diaphragm Fatigue in SMNΔ7 Mice and Its Molecular Determinants: An Underestimated Issue. Int J Mol Sci 24:N/A (2023). PubMed: 37834400
- Mesquita PHC et al. Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats. Physiol Rep 10:e15542 (2022). PubMed: 36543327