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AB181862

Anti-TRAX 抗体 [EPR13929(B)]

Anti-TRAX antibody [EPR13929(B)]

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(1 Publication)

Rabbit Recombinant Monoclonal TRAX antibody. Suitable for IP, WB, ICC/IF and reacts with Human, Mouse, Rat samples. Cited in 1 publication.

別名を表示する

TRAX, TSNAX, Translin-associated protein X, Translin-associated factor X

4 Images
Immunocytochemistry/ Immunofluorescence - Anti-TRAX antibody [EPR13929(B)] (AB181862)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-TRAX antibody [EPR13929(B)] (AB181862)

Immunofluorescent analysis of HeLa cells (-20°C Acetone-fixed) labeling TRAX with ab181862 at 1/100 dilution followed by Goat anti rabbit IgG (Alexa Fluor®488) secondary at 1/200 dilution and counter-stained with DAPI (blue).

Immunoprecipitation - Anti-TRAX antibody [EPR13929(B)] (AB181862)
  • IP

Supplier Data

Immunoprecipitation - Anti-TRAX antibody [EPR13929(B)] (AB181862)

Western blot analysis of immunoprecipitation pellet from Human testis lysate immunoprecipitated using ab181862 at 1/60 dilution.
Secondary : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution.

All lanes:

Immunoprecipitation - Anti-TRAX antibody [EPR13929(B)] (ab181862)

Predicted band size: 33 kDa

false

Western blot - Anti-TRAX antibody [EPR13929(B)] (AB181862)
  • WB

Supplier Data

Western blot - Anti-TRAX antibody [EPR13929(B)] (AB181862)

All lanes:

Western blot - Anti-TRAX antibody [EPR13929(B)] (ab181862) at 1/5000 dilution

All lanes:

Human testis lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab136636'>ab136636</a>) at 1/500 dilution

Predicted band size: 33 kDa

false

Western blot - Anti-TRAX antibody [EPR13929(B)] (AB181862)
  • WB

Supplier Data

Western blot - Anti-TRAX antibody [EPR13929(B)] (AB181862)

All lanes:

Western blot - Anti-TRAX antibody [EPR13929(B)] (ab181862) at 1/20000 dilution

Lane 1:

Mouse testis lysate at 20 µg

Lane 2:

Rat testis lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 106 kDa,24 kDa,33 kDa,52 kDa

Observed band size: 110 kDa,25 kDa

false

関連する標識済み抗体及び組成の異なる製品 (1)

  • Carrier free

    Anti-TRAX antibody [EPR13929(B)] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR13929(B)

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Rat, Human

アプリケーション

IP, ICC/IF, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/60", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/20000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/20000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/20000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

出荷温度及び保存条件

製品の状態
Liquid
精製度
Tissue culture supernatant
バッファー組成
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The protein TRAX also known as Translin-associated factor X functions mechanically as an RNA-binding protein. It plays a role in binding to specific RNA sequences and is involved in RNA transport and stability. The protein has an approximate molecular weight of 31 kDa. TRAX is expressed in various tissues including brain testis and hematopoietic tissues indicating its involvement in diverse biological processes.
Biological function summary

TRAX interacts with Translin to form a heteromeric complex that is involved in mRNA regulation. The complex participates in the regulation of neural development and synaptic plasticity by stabilizing mRNA and modulating its translation. TRAX’s involvement in RNA processing suggests it may have implications in cellular growth and response to stress.

Pathways

TRAX participates in the RNA regulatory network including the MAPK signaling pathway. It influences stress responses and cell survival by associating with proteins like Translin. This pathway coordination ensures cells can adapt to environmental changes efficiently important in maintaining neuronal health.

TRAX has links to neurodegenerative diseases and certain cancers. Alterations in TRAX expression or function can contribute to conditions such as schizophrenia. Its interaction with proteins in disease contexts including Translin suggests that misregulation of the TRAX-Translin complex may play a role in the pathology by impairing RNA transport and stability disrupting cellular functions.

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis.
See full target information TSNAX

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Pakistan journal of pharmaceutical sciences 38:1632-1646 PubMed40996179

2025

Cantharidic acid inhibits the malignant progression of colorectal cancer by inhibiting aerobic glycolysis and regulating the PI3K/Akt/P53 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wei,Shulin Dai,Dongyun Zhang,Ting Zhang,Xiaoyu Wang,Bolin Liu,Wei Huang,Yin Li,Mingliao Niu
View all publications

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