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Anti-TRAP220/MED1 抗体 (ab84386)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)

Key features and details

  • Rabbit polyclonal to TRAP220/MED1
  • Suitable for: IHC-P
  • Reacts with: Mouse, Human
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-TRAP220/MED1 antibody
    TRAP220/MED1 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to TRAP220/MED1

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: IHC-Pmore details

  • 種交差性

    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • Human breast tumor and mouse squamous cell carcinoma tissues.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab84386の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-P
1/100 - 1/500.

Epitope exposure with citrate buffer will enhance staining.
特記事項
IHC-P
1/100 - 1/500.

Epitope exposure with citrate buffer will enhance staining.

ターゲット情報

  • 機能

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

  • 組織特異性

    Ubiquitously expressed.

  • 配列類似性

    Belongs to the Mediator complex subunit 1 family.

  • 翻訳後修飾

    Phosphorylated by MAPK1 or MAPK3 during G2/M phase which may enhance protein stability and promote entry into the nucleolus. Phosphorylated upon DNA damage, probably by ATM or ATR.

  • 細胞内局在

    Nucleus. A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
  • Information by UniProt

  • 参照データベース

    • 別名

      • Activator-recruited cofactor 205 kDa component antibody
      • ARC205 antibody
      • CRSP1 antibody
      • CRSP200 antibody
      • DRIP205 antibody
      • DRIP230 antibody
      • MED1 antibody
      • MED1_HUMAN antibody
      • Mediator complex subunit 1 antibody
      • Mediator of RNA polymerase II transcription subunit 1 antibody
      • p53 regulatory protein RB18A antibody
      • PBP antibody
      • Peroxisome proliferator-activated receptor-binding protein antibody
      • PPAR binding protein antibody
      • PPAR-binding protein antibody
      • PPARBP antibody
      • PPARGBP antibody
      • RB18A antibody
      • Thyroid hormone receptor-associated protein complex 220 kDa component antibody
      • Thyroid receptor-interacting protein 2 antibody
      • TR-interacting protein 2 antibody
      • Trap220 antibody
      • TRIP-2 antibody
      • TRIP2 antibody
      • Vitamin D receptor-interacting protein complex component DRIP205 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)
      ab84386 at 1/250 dilution staining TRAP220/MED1 in human breast tumor by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP220/MED1 antibody (ab84386)
      ab84386 at 1/250 dilution staining TRAP220/MED1 in mouse squamous cell carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

    参考文献 (0)

    ab84386 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab84386 は論文での使用が確認できていません。

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