Anti-TP53INP1 抗体 (ab9775)
Key features and details
- Rabbit polyclonal to TP53INP1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-TP53INP1 antibody
TP53INP1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TP53INP1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human TP53INP1 aa 1-100.
(Peptide available asab9776) -
ポジティブ･コントロール
- Human lung, human spleen,tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9775の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
Use a concentration of 1 - 2 µg/ml. Can be blocked with Human TP53INP1 peptide (ab9776).
Human lung tissue lysate can be used as a positive control and a band at 27 kDa can be detected. A lower band at 18 kDa was detected in human spleen, tissue lysates. |
| IHC-P |
Use a concentration of 5 µg/ml.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Can be blocked with Human TP53INP1 peptide (ab9776). Human lung tissue lysate can be used as a positive control and a band at 27 kDa can be detected. A lower band at 18 kDa was detected in human spleen, tissue lysates. |
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IHC-P
Use a concentration of 5 µg/ml. |
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TP53INP1 antibody (ab9775)
Immunohistochemistry (Formalin-fixed paraffin embedded sections) of human liver tissue labelingp53 DINP1/TP53INP1 with Anti-p53 DINP1/TP53INP1 antibody (ab9775) at 5μg/ml.
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Western blot - Anti-TP53INP1 antibody (ab9775)Western blot analysis of p53DINP1 expression in human lung tissue lysate with anti-p53DINP1 (ab9775) at 2
Western blot analysis of p53DINP1 expression in human lung tissue lysate with anti-p53DINP1 (ab9775) at 2 µg/ml in the absence (lane 1) or presence (lane 2) of blocking peptide (ab9776).µ g/ml in the absence (lane 1) or presence (lane 2) of blocking peptide (ab9776).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (8)
ab9775 は 8 報の論文で使用されています。
- Tu Y et al. Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract. Exp Eye Res 199:108185 (2020). PubMed: 32841649
- Fang Y et al. Exosomal miRNA-106b from cancer-associated fibroblast promotes gemcitabine resistance in pancreatic cancer. Exp Cell Res 383:111543 (2019). PubMed: 31374207
- Gao F & Wang W MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a. Mol Med Rep 11:1200-6 (2015). PubMed: 25369914
- Zhang J et al. microRNA-155 acts as an oncogene by targeting the tumor protein 53-induced nuclear protein 1 in esophageal squamous cell carcinoma. Int J Clin Exp Pathol 7:602-10 (2014). WB, IHC-P ; Human . PubMed: 24551280
- Wang Y et al. Overexpression of SIRT1 promotes high glucose-attenuated corneal epithelial wound healing via p53 regulation of the IGFBP3/IGF-1R/AKT pathway. Invest Ophthalmol Vis Sci 54:3806-14 (2013). PubMed: 23661372
- Polioudakis D et al. A Myc-microRNA network promotes exit from quiescence by suppressing the interferon response and cell-cycle arrest genes. Nucleic Acids Res 41:2239-54 (2013). WB . PubMed: 23303785
- Zhou Y et al. Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway. Hum Mol Genet : (2011). WB ; Rat . PubMed: 21965303
- Jiang F et al. MiR-125b promotes proliferation and migration of type II endometrial carcinoma cells through targeting TP53INP1 tumor suppressor in vitro and in vivo. BMC Cancer 11:425 (2011). WB ; Human . PubMed: 21970405