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AB89624

Anti-TOM70 抗体

Anti-TOM70 antibody

5

(1 Review)

|

(4 Publications)

Mouse Polyclonal TOM70 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TOMM70.

別名を表示する

KIAA0719, TOM70, TOMM70A, TOMM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, Translocase of outer mitochondrial membrane protein 70

3 Images
Western blot - Anti-TOM70 antibody (AB89624)
  • WB

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

All lanes:

human liver tissue lysate at 50 µg

Predicted band size: 67 kDa

Observed band size: 67 kDa

false

Western blot - Anti-TOM70 antibody (AB89624)
  • WB

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

All lanes:

HepG2 cell lysate at 50 µg

Predicted band size: 67 kDa

Observed band size: 75 kDa

false

Western blot - Anti-TOM70 antibody (AB89624)
  • WB

Unknown

Western blot - Anti-TOM70 antibody (AB89624)

All lanes:

Western blot - Anti-TOM70 antibody (ab89624) at 1 µg/mL

Lane 1:

TOMM70A transfected 293T cell lysate at 25 µg

Lane 2:

Non transfected 293T cell lysate at 25 µg

Predicted band size: 67 kDa

Observed band size: 75 kDa

false

Key facts

宿主種

Mouse

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

Yes

交差種

Human

アプリケーション

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Human TOMM70.

O94826

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }
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下記製品にもご興味をお持ちいただけるかもしれません:

AB113852

TMRE-Mitochondrial Membrane Potential Assay Kit

5

4 Reviews

製品ページを見る
こちらの製品も推奨する理由

この製品は、同様の実験や関連する研究で広く使用されていることから推奨させていただいております。

お客様の実験に適するかご確認いただくため、必ず製品データシートをご確認いただくことをお勧めいたします。ご不明点等ございましたら、テクニカルサポートチームまでお問い合わせください。

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.4 Constituents: 100% PBS
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Acts as a receptor of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) (PubMed : 12526792). Recognizes and mediates the translocation of mitochondrial preproteins from the cytosol into the mitochondria in a chaperone dependent manner (PubMed : 12526792, PubMed : 35025629). Mediates TBK1 and IRF3 activation induced by MAVS in response to Sendai virus infection and promotes host antiviral responses during virus infection (PubMed : 20628368, PubMed : 25609812, PubMed : 32728199). Upon Sendai virus infection, recruits HSP90AA1 : IRF3 : BAX in mitochondrion and the complex induces apoptosis (PubMed : 25609812).
See full target information TOMM70
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文献 (4)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 8:617762 PubMed33537307

2021

Interplay Between Mitophagy and Apoptosis Defines a Cell Fate Upon Co-treatment of Breast Cancer Cells With a Recombinant Fragment of Human κ-Casein and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand.

Applications

Unspecified application

Species

Unspecified reactive species

Fabian Wohlfromm,Max Richter,Lado Otrin,Kamil Seyrek,Tanja Vidaković-Koch,Elena Kuligina,Vladimir Richter,Olga Koval,Inna N Lavrik

PLoS genetics 16:e1008923 PubMed32735630

2020

RCC1L (WBSCR16) isoforms coordinate mitochondrial ribosome assembly through their interaction with GTPases.

Applications

Unspecified application

Species

Unspecified reactive species

Aurelio Reyes,Paola Favia,Sara Vidoni,Vittoria Petruzzella,Massimo Zeviani

Cancers 12: PubMed32486420

2020

The Recombinant Fragment of Human κ-Casein Induces Cell Death by Targeting the Proteins of Mitochondrial Import in Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Max Richter,Fabian Wohlfromm,Thilo Kähne,Hannes Bongartz,Kamil Seyrek,Yuriy Kit,Olga Chinak,Vladimir A Richter,Olga A Koval,Inna N Lavrik

The Journal of biological chemistry 288:2223-37 PubMed23212910

2012

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

Applications

WB

Species

Human

Aleksandar Rakovic,Katharina Shurkewitsch,Philip Seibler,Anne Grünewald,Alessandra Zanon,Johann Hagenah,Dimitri Krainc,Christine Klein
View all publications
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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
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関連製品

Select an associated product type
Alternative Product
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0

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