Anti-TNFRSF14/HVEM 抗体 (ab62462)
Key features and details
- Rabbit polyclonal to TNFRSF14/HVEM
- Suitable for: WB, ICC
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TNFRSF14/HVEM antibody
TNFRSF14/HVEM 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TNFRSF14/HVEM -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICCmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human TNFRSF14/HVEM (C terminal).
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ポジティブ･コントロール
- Raji cell lysate. Raji cells.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab62462の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa).
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| ICC |
Use a concentration of 10 - 20 µg/ml.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 31 kDa). |
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ICC
Use a concentration of 10 - 20 µg/ml. |
ターゲット情報
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機能
Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. -
組織特異性
Widely expressed, with the highest expression in lung, spleen and thymus. -
配列類似性
Contains 3 TNFR-Cys repeats. -
翻訳後修飾
N-glycosylated. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 8764 Human
- Omim: 602746 Human
- SwissProt: Q92956 Human
- Unigene: 512898 Human
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別名
- HVEML antibody
- ATAR antibody
- CD270 antibody
see all
画像
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Western blot - Anti-TNFRSF14/HVEM antibody (ab62462)All lanes : Anti-TNFRSF14/HVEM antibody (ab62462) at 2 µg/ml
Lane 1 : Raji cell lysate with no blocking peptide
Lane 2 : Raji cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 31 kDa
Observed band size: 27 kDa why is the actual band size different from the predicted? -
Immunocytochemistry - Anti-TNFRSF14/HVEM antibody (ab62462)Immunocytochemistry of TNFRSF14/HVEM in Raji cells with ab62462 antibody at 10 µg/ml.
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Immunocytochemistry - Anti-TNFRSF14/HVEM antibody (ab62462)Immunofluorescence of TNFRSF14/HVEM in Raji cells using ab62462 at 20 ug/ml.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab62462 は 1 報の論文で使用されています。
- Duan L et al. HVEM/HIF-1a promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions. J Ovarian Res 13:40 (2020). PubMed: 32312328