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AB11564

Anti-TNF alpha 抗体 [MP6-XT3]

Anti-TNF alpha antibody [MP6-XT3]

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(12 Publications)

Rat Monoclonal TNF alpha antibody. Suitable for ELISA and reacts with Recombinant fragment - Mouse samples. Cited in 12 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Mouse Tnf.

別名を表示する

Tnfa, Tnfsf2, Tnf, Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a

1 Images
ELISA - Anti-TNF alpha antibody [MP6-XT3] (AB11564)
  • ELISA

Unknown

ELISA - Anti-TNF alpha antibody [MP6-XT3] (AB11564)

Recombinant Mouse TNF alpha detected in a sandwich assay with Rat anti Mouse TNF alpha (ab11564) as the coating antibody; Rabbit anti Mouse TNF alpha : Biotin as the detetction antibody and Streptavidin : HRP as the final layer.

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

MP6-XT3

アイソタイプ

IgG1

キャリアフリー

No

アプリケーション

ELISA

applications

免疫原

Recombinant Full Length Protein corresponding to Mouse Tnf.

P06804

特異性

ab11564 recognises murine TNF alpha. Reactivity with murine TNF Beta has not yet been determined.

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代替製品

Primary Antibodies

AB215188

Anti-TNF alpha antibody [EPR20972]

KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-TNF alpha antibody [EPR20972] (AB215188)

  • 0
  • 1
Primary Antibodies

AB222500

Anti-TNF alpha antibody [EPR19147] - Low endotoxin, Azide free

RabMAb|Recombinant|KO Validated

Immunoprecipitation - Anti-TNF alpha antibody [EPR19147] - Low endotoxin, Azide free (AB222500)

  • 0
  • 0
Primary Antibodies

AB225576

Anti-TNF alpha antibody [EPR20972] - BSA and Azide free

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-TNF alpha antibody [EPR20972] - BSA and Azide free (AB225576)

  • 0
  • 0
Primary Antibodies

AB237355

PE Anti-TNF alpha antibody [EPR20972]

RabMAb|Recombinant|Trial Size

Flow Cytometry (Intracellular) - PE Anti-TNF alpha antibody [EPR20972] (AB237355)

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  • 0
Primary Antibodies

AB66579

Anti-TNF alpha antibody

Lab Essentials

Western blot - Anti-TNF alpha antibody (AB66579)

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Primary Antibodies

AB183218

Anti-TNF alpha antibody [EPR19147]

20ul selling size|KO Validated|RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-TNF alpha antibody [EPR19147] (AB183218)

  • 5
  • 1

組合せ製品

Primary Antibodies

AB283818

Anti-IL-1 beta antibody [RM1009]

BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunocytochemistry - Anti-IL-1 beta antibody [RM1009] (AB283818)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Primary Antibodies

AB259341

Anti-IL-6 antibody [EPR23819-11]

20ul selling size|RabMAb|Recombinant

Immunoprecipitation - Anti-IL-6 antibody [EPR23819-11] (AB259341)

  • 0
  • 0
Primary Antibodies

AB9485

Anti-GAPDH antibody - Loading Control

BOND RX™ Validated|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-GAPDH antibody - Loading Control (AB9485)

  • 5
  • 88
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant fragment - Mouse": { "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "1/5", "ELISA-species-notes": "<p></p>" } } }
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製品の詳細

This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
精製に関する特記事項
Purified IgG prepared by affinity chromatography from tissue culture supernatant.
バッファー組成
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (PubMed : 25586176). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity). Promotes osteoclastogenesis and therefore mediates bone resorption (PubMed : 32741026).. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
See full target information Tnf
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文献 (12)

Recent publications for all applications. Explore the full list and refine your search

Journal of biochemical and molecular toxicology 37:e23279 PubMed36541345

2022

The capsaicinoid nonivamide suppresses the inflammatory response and attenuates the progression of steatosis in a NAFLD-rat model.

Applications

Unspecified application

Species

Unspecified reactive species

Naruemon Wikan,Jiraporn Tocharus,Chio Oka,Sivanan Sivasinprasasn,Waraluck Chaichompoo,Apichart Suksamrarn,Chainarong Tocharus

Journal of cellular physiology 237:1818-1832 PubMed34825376

2021

Melatonin attenuates reactive astrogliosis and glial scar formation following cerebral ischemia and reperfusion injury mediated by GSK-3β and RIP1K.

Applications

Unspecified application

Species

Unspecified reactive species

Nuttapong Yawoot,Jirakhamon Sengking,Piyawadee Wicha,Piyarat Govitrapong,Chainarong Tocharus,Jiraporn Tocharus

Synapse (New York, N.Y.) 75:e22219 PubMed34269482

2021

Propofol alleviates neuropathic pain in chronic constriction injury rat models via the microRNA-140-3p/Jagged-1 peptide/Notch signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Fang Cheng,Wei Qin,Ai-Xing Yang,Feng-Feng Yan,Yu Chen,Jian-Xin Ma

Frontiers in pharmacology 12:637273 PubMed33912052

2021

Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach.

Applications

Unspecified application

Species

Unspecified reactive species

Yunteng Xu,Hui Li,Xiaojuan He,Yanfeng Huang,Shengjie Wang,Lili Wang,Changlong Fu,Hongzhi Ye,Xihai Li,Tetsuya Asakawa

Experimental and therapeutic medicine 20:3782-3790 PubMed32855727

2020

Transcriptomic study of lipopolysaccharide-induced sepsis damage in a mouse heart model.

Applications

Unspecified application

Species

Unspecified reactive species

Cunrong Chen,Junting Weng,Dexiang Fang,Jianfei Chen,Min Chen

Evidence-based complementary and alternative medic 2020:9189457 PubMed32104199

2020

Improving Small Intestinal Motility in Experimental Acute Necrotising Pancreatitis by Modulating the CPI-17/MLCP Pathway Using Chaiqin Chengqi Decoction.

Applications

Unspecified application

Species

Unspecified reactive species

Ziqi Lin,Chenlong Zhang,Xiaoxin Zhang,Na Shi,Yongjian Wen,Chengxia Han,Dan Du,Tingting Liu,Tao Jin,Lihui Deng,Kun Jiang,Xiaonan Yang,Jia Guo,Anthony Philips,Robert Sutton,John A Windsor,Wei Huang,Ping Xue,Qing Xia

eLife 7: PubMed29993362

2018

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.

Applications

Unspecified application

Species

Unspecified reactive species

Jia-Ren Lin,Benjamin Izar,Shu Wang,Clarence Yapp,Shaolin Mei,Parin M Shah,Sandro Santagata,Peter K Sorger

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 22:17-21 PubMed29302208

2018

Morroniside on anti-inflammation activities in rats following acute myocardial infarction.

Applications

Unspecified application

Species

Unspecified reactive species

Bangxing Yu,Guoxing Zhang,Yi An,Wen Wang

Molecular medicine reports 13:1010-8 PubMed26648171

2015

Lentivirus-mediated TNF-α gene silencing and overexpression of osteoprotegerin inhibit titanium particle-induced inflammatory response and osteoclastogenesis in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Li Peng,Hongzhi Wang,Keguan Song,Hai Wang,Ping Liu

PloS one 10:e0117498 PubMed25793256

2015

Tempol treatment reduces anxiety-like behaviors induced by multiple anxiogenic drugs in rats.

Applications

WB

Species

Rat

Gaurav Patki,Ankita Salvi,Hesong Liu,Fatin Atrooz,Isam Alkadhi,Matthew Kelly,Samina Salim
View all publications
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