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AB188442

Anti-TMEM56 抗体 - C-terminal

Anti-TMEM56 antibody - C-terminal

4

(1 Review)

|

(1 Publication)

Rabbit Polyclonal TMEM56 antibody. C-terminal. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus.

別名を表示する

TMEM56, TLCD4, TLC domain-containing protein 4, Transmembrane protein 56

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-TMEM56 antibody - C-terminal (AB188442)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-TMEM56 antibody - C-terminal (AB188442)

U-2 OS cells stained for TMEM56 (green) using ab188442 at 2 μg/ml in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM56 antibody - C-terminal (AB188442)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEM56 antibody - C-terminal (AB188442)

Immunohistochemical analysis of paraffin embedded Human uterus, pre-menopause tissue labeling TMEM56 with ab188442 at 1/200.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

ICC/IF, IHC-P

applications

免疫原

Recombinant Fragment Protein within Human TLCD4 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q96MV1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

TMEM56 also known as Transmembrane Protein 56 has a mass of approximately 43 kDa. It functions as a transmembrane protein that spans the cell membrane. The protein participates in cellular signaling by allowing or facilitating interaction across the membrane. TMEM56 is expressed in various tissues including the lungs heart and placenta. Its membrane-spanning capabilities suggest a role in linking extracellular signals to intracellular responses.
Biological function summary

The role of TMEM56 involves regulation of cellular growth and differentiation processes. It may also interact with other membrane-associated proteins as part of the cellular response complex. By engaging in these processes TMEM56 influences important cellular dynamics that maintain tissue homeostasis and proper cellular function.

Pathways

TMEM56 integrates into signal transduction pathways associated with cellular proliferation and differentiation. It participates in the MAPK/ERK pathway which is important for transmitting extracellular signals into cellular responses. In this context TMEM56 interacts with components like MEK and ERK influencing cell fate decisions and responses to external stimuli.

TMEM56 shows an association with certain types of cancer particularly in its involvement in deregulated cell signaling. Alterations in TMEM56 expression levels or function can disrupt normal cellular signaling contributing to oncogenic processes. Additionally altered expression of TMEM56 connects to neurodegenerative disorders possibly through pathways shared with proteins like Tau which is implicated in conditions like Alzheimer’s disease.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

See full target information TLCD4
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Nature structural & molecular biology 30:1141-1152 PubMed37386215

2023

Hierarchical TAF1-dependent co-translational assembly of the basal transcription factor TFIID.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Bernardini,Pooja Mukherjee,Elisabeth Scheer,Ivanka Kamenova,Simona Antonova,Paulina Karen Mendoza Sanchez,Gizem Yayli,Bastien Morlet,H T Marc Timmers,László Tora
View all publications
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Abcam product promise

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