Anti-TLE4 抗体 (ab64833)
Key features and details
- Rabbit polyclonal to TLE4
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-TLE4 antibody -
製品の詳細
Rabbit polyclonal to TLE4 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human -
免疫原
Synthetic peptide corresponding to Human TLE4 (internal sequence).
Database link: Q04727 -
ポジティブ･コントロール
- WB: Jurkat, 293, HuvEc cell; rat muscle lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab64833の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
1/500 - 1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 84 kDa).
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| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 84 kDa). |
ターゲット情報
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関連性
TLE4 (Transducin-like enhancer protein 4) is a member of the Groucho family of transcriptional corepressors and inhibits the transcriptional activation mediated by Pax5 and by beta-catenin and TCF family members in Wnt signaling. -
細胞内局在
Nuclear -
参照データベース
- Entrez Gene: 7091 Human
- Entrez Gene: 25565 Rat
- Omim: 605132 Human
- SwissProt: Q04727 Human
- SwissProt: Q07141 Rat
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別名
- B lymphocyte gene 1 antibody
- E(sp1) homolog Drosophila antibody
- E(spI) antibody
see all
画像
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Western blot - Anti-TLE4 antibody (ab64833)All lanes : Anti-TLE4 antibody (ab64833) at 1/500 dilution
Lane 1 : Jurkat cell extract at 30 µg
Lane 2 : 293 cell extract at 30 µg
Lane 3 : HuvEc cell extract at 30 µg
Lane 4 : HuvEc cell extract immunising peptide at 10 µg
Predicted band size: 84 kDa
Observed band size: 84 kDa -
Western blot - Anti-TLE4 antibody (ab64833)Anti-TLE4 antibody (ab64833) at 1/1000 dilution + Rat muscle lysate
Predicted band size: 84 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab64833 は 4 報の論文で使用されています。
- Wakhloo D et al. Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin. Nat Commun 11:1313 (2020). PubMed: 32152318
- Patel D et al. The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex. PLoS One 13:e0191689 (2018). PubMed: 29370269
- Bandyopadhyay S et al. Tle4 regulates epigenetic silencing of gamma interferon expression during effector T helper cell tolerance. Mol Cell Biol 34:233-45 (2014). PubMed: 24190972
- Wheat JC et al. The corepressor tle4 is a novel regulator of murine hematopoiesis and bone development. PLoS One 9:e105557 (2014). WB ; Mouse . PubMed: 25153823