Anti-TIPE2 抗体 (ab169616)
Key features and details
- Mouse polyclonal to TIPE2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TIPE2 antibody
TIPE2 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to TIPE2 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Rabbit, Cow, Baboon
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免疫原
Recombinant full length protein within Human TIPE2 aa 1 to the C-terminus. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: AAH63014 -
ポジティブ･コントロール
- WB: TIPE2 transfected HEK-293T cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.4
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab169616の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. |
ターゲット情報
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機能
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis. -
配列類似性
Belongs to the TNFAIP8 family. TNFAIP8L2 subfamily. -
ドメイン
The central region was initially thought to constitute a DED (death effector) domain. However, 3D-structure data reveal a previously uncharacterized fold that is different from the predicted fold of a DED (death effector) domain. It consists of a large, hydrophobic central cavity that is poised for cofactor binding. - Information by UniProt
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参照データベース
- Entrez Gene: 510652 Cow
- Entrez Gene: 79626 Human
- Entrez Gene: 69769 Mouse
- Entrez Gene: 100328663 Rabbit
- Entrez Gene: 310663 Rat
- Omim: 612112 Human
- SwissProt: A9X192 Baboon
- SwissProt: Q3ZBK5 Cow
see all -
別名
- AW610835 antibody
- FLJ23467 antibody
- Inflammation factor 20 antibody
see all
画像
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Western blot - Anti-TIPE2 antibody (ab169616)All lanes : Anti-TIPE2 antibody (ab169616) at 1 µg/ml
Lane 1 : TIPE2 transfected HEK-293T cell lysate
Lane 2 : Non-transfected HEK-293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 21 kDa
データシートおよび資料
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Datasheet download
参考文献 (1)
ab169616 は 1 報の論文で使用されています。
- He B et al. Construction of a lentiviral vector containing shRNA targeting ADAM17 and its role in attenuating endotoxemia in mice. Mol Med Rep 16:6013-6019 (2017). PubMed: 28849138
