Anti-Thyroid Hormone Receptor alpha 抗体 [EPR7862] (ab179438)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR7862] to Thyroid Hormone Receptor alpha
- Suitable for: WB
- Reacts with: Mouse, Human
Related conjugates and formulations
製品の概要
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製品名
Anti-Thyroid Hormone Receptor alpha antibody [EPR7862]
Thyroid Hormone Receptor alpha 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR7862] to Thyroid Hormone Receptor alpha -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- WB: Jurkat, MEF, NIH/3T3, Molt-4 and MCF-7 cell lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR7862 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab179438の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/5000. Predicted molecular weight: 55 kDa.
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特記事項 |
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WB
1/1000 - 1/5000. Predicted molecular weight: 55 kDa. |
ターゲット情報
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機能
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. -
関連疾患
Hypothyroidism, congenital, non-goitrous, 6 -
配列類似性
Belongs to the nuclear hormone receptor family. NR1 subfamily.
Contains 1 nuclear receptor DNA-binding domain. -
ドメイン
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 7067 Human
- Entrez Gene: 21833 Mouse
- Omim: 190120 Human
- SwissProt: P10827 Human
- SwissProt: P63058 Mouse
- Unigene: 724 Human
- Unigene: 265917 Mouse
- Unigene: 442648 Mouse
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別名
- AR7 antibody
- c-erbA-1 antibody
- C-erbA-alpha antibody
see all
画像
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All lanes : Anti-Thyroid Hormone Receptor alpha antibody [EPR7862] (ab179438) at 0.546 µg/ml
Lane 1 : Jurkat (Human T cell leukemia T lymphocyte) cell lysate
Lane 2 : NIH/3T3(Mouse embryonic fibroblast) whole cell lysate
Lane 3 : MEF (Mouse embryonic fibroblast) cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 0.05 µg/ml
Predicted band size: 55 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab179438 は論文での使用が確認できていません。