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リコンビナントRabMAb

Anti-Thromboxane synthase 抗体 [EPR7333(2)] (ab157481)

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Western blot - Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)
  • Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR7333(2)] to Thromboxane synthase
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-Thromboxane synthase antibody [EPR7333(2)]
    Thromboxane synthase 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR7333(2)] to Thromboxane synthase

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details
    適用なし: ICC/IF,IHC-P or IP

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • WI38 and fetal liver lysates.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab157481の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/5000. Predicted molecular weight: 61 kDa.
特記事項
WB
1/1000 - 1/5000. Predicted molecular weight: 61 kDa.
追加情報
Is unsuitable for ICC/IF,IHC-P or IP.

ターゲット情報

  • 組織特異性

    Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.

  • 関連疾患

    Defects in TBXAS1 are the cause of Ghosal hematodiaphyseal dysplasia (GHDD) [MIM:231095]. GHDD is a rare autosomal recessive disorder characterized by increased bone density with predominant diaphyseal involvement and aregenerative corticosteroid-sensitive anemia. Aregenerative anemia is characterized by bone marrow failure, so that functional marrow cells are regenerated slowly or not at all.
    Defects in TBXAS1 are the cause of thromboxane synthetase deficiency (TBXAS1 deficiency) [MIM:274180]. It is characterized by hemorrhagic diathesis.

  • 配列類似性

    Belongs to the cytochrome P450 family.

  • 細胞内局在

    Endoplasmic reticulum membrane.
  • Information by UniProt

  • 参照データベース

    • 別名

      • BDPLT14 antibody
      • CYP5 antibody
      • CYP5A1 antibody
      • Cytochrome P450 5A1 antibody
      • Cytochrome P450, family 5, subfamily A, polypeptide 1 antibody
      • FLJ52771 antibody
      • GHOSAL antibody
      • Platelet cytochrome P450 subfamily V antibody
      • Tbxas1 antibody
      • THAS antibody
      • THAS_HUMAN antibody
      • Thromboxane A synthase 1 (platelet) antibody
      • Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) antibody
      • Thromboxane A synthase 1 antibody
      • Thromboxane A synthase 1 platelet cytochrome P450 subfamily V antibody
      • Thromboxane-A synthase antibody
      • TS antibody
      • TXA synthase antibody
      • TXAS antibody
      • TXS antibody
      see all

    画像

    • Western blot - Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)
      Western blot - Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)
      All lanes : Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481) at 1/1000 dilution

      Lane 1 : WI38 cell lysate
      Lane 2 : Fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 61 kDa

    • Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)
      Anti-Thromboxane synthase antibody [EPR7333(2)] (ab157481)

    参考文献 (2)

    ab157481 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab157481 は 2 報の論文で使用されています。

    • Liu W  et al. Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics. Front Immunol 13:963123 (2022). PubMed: 36016933
    • Cianciaruso C  et al. Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles. Cell Rep 27:3062-3080.e11 (2019). PubMed: 31167148

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