Anti-Thomsen-Friedenreich Antigen 抗体 [SPM320], prediluted (ab17785)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)](https://www.abcam.co.jp/ps/products/17/ab17785/Images/ab17785-26579-anti-thomsen-friedenreich-antigen-antibody-spm320-prediluted-immunohistochemistry.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)")
Key features and details
- Mouse monoclonal [SPM320] to Thomsen-Friedenreich Antigen, prediluted
- Suitable for: IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgM
製品の概要
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製品名
Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted
Thomsen-Friedenreich Antigen 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [SPM320] to Thomsen-Friedenreich Antigen, prediluted -
由来種
Mouse -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Tissue, cells or virus corresponding to Human Thomsen-Friedenreich Antigen.
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エピトープ
Galß1-3GalNAc -
ポジティブ･コントロール
- KG1 cells. Human colorectal carcinoma tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: Tris buffered saline, 1% BSA -
Concentration information loading... -
精製度
Purified IgM -
ポリ/モノ
モノクローナル -
クローン名
SPM320 -
アイソタイプ
IgM -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab17785の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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| 特記事項 |
|---|
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IHC-P
Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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関連性
The Thomsen Friedenreich antigen acts as an oncofoetal antigen, with low expression in normal adult tissues but increasing to foetal levels of expression in hyperplasia or malignancy. It is considered as a pan carcinoma marker. Can be applied for the detection of cells with TF antigen and is especially applicable for sensitive determination of neuraminidases. -
細胞内局在
Cell Membrane -
別名
- CD176 antibody
- TF antibody
- TF antigen antibody
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Thomsen-Friedenreich Antigen antibody [SPM320], prediluted (ab17785)Human colon adenocarcinoma stained with ab17785 (prediluted)
データシートおよび資料
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Datasheet download
参考文献 (3)
ab17785 は 3 報の論文で使用されています。
- Saha S et al. Mangiferin attenuates oxidative stress induced renal cell damage through activation of PI3K induced Akt and Nrf-2 mediated signaling pathways. Biochem Biophys Rep 5:313-327 (2016). PubMed: 28955838
- Bhattacharyya S et al. Amelioration of aspirin induced oxidative impairment and apoptotic cell death by a novel antioxidant protein molecule isolated from the herb Phyllanthus niruri. PLoS One 9:e89026 (2014). Mouse . PubMed: 24586486
- Kumagai H et al. Multifunctional nanobeacon for imaging Thomsen-Friedenreich antigen-associated colorectal cancer. Int J Cancer : (2012). Human . PubMed: 23055136
