Anti-TGF beta 2 抗体 (ab53778)
Key features and details
- Rabbit polyclonal to TGF beta 2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-TGF beta 2 antibody
TGF beta 2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to TGF beta 2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Synthetic peptide derived from human TGF beta 2
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ポジティブ･コントロール
- Human lung carcinoma tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53778の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. -
関連疾患
A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly. Translocation t(1;7)(q41;p21) with HDAC9.
Loeys-Dietz syndrome 4
Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). NSAD is a frequently asymptomatic but potentially lethal disease characterized by thoracic aortic aneurysms and dissections without additional syndromic features. -
配列類似性
Belongs to the TGF-beta family. -
翻訳後修飾
The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 7040 Human
- Entrez Gene: 7042 Human
- Entrez Gene: 7043 Human
- Entrez Gene: 21803 Mouse
- Entrez Gene: 21808 Mouse
- Entrez Gene: 25717 Rat
- Entrez Gene: 59086 Rat
- Entrez Gene: 81809 Rat
see all -
別名
- BSC-1 cell growth inhibitor antibody
- BSC1 cell growth inhibitor antibody
- Cetermin antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TGF beta 2 antibody (ab53778)Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using ab53778 at a 1/50 dilution.
Left image un-treated.
Right image treated with immunising peptide.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab53778 は 4 報の論文で使用されています。
- Ji F et al. Tumor Microenvironment Characterization in Breast Cancer Identifies Prognostic and Neoadjuvant Chemotherapy Relevant Signatures. Front Mol Biosci 8:759495 (2021). PubMed: 34708079
- Yang P et al. Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection. Biochem Res Int 2020:6285987 (2020). PubMed: 32802507
- Ofiteru AM et al. Qualifying Osteogenic Potency Assay Metrics for Human Multipotent Stromal Cells: TGF-ß2 a Telling Eligible Biomarker. Cells 9:N/A (2020). PubMed: 33260388
- Villafan-Bernal JR et al. Molecular profiling of a simple rat model of open tibial fractures with hematoma and periosteum disruption. Exp Ther Med 12:3261-3267 (2016). PubMed: 27882147