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Anti-TBLR1/TBL1XR1 抗体 (ab24550)

Reviews (2)Q&A (1)References (13)
Western blot - Anti-TBLR1/TBL1XR1 antibody (ab24550)

    Key features and details

    • Rabbit polyclonal to TBLR1/TBL1XR1
    • Suitable for: WB
    • Reacts with: Human
    • Isotype: IgG

    製品の概要

    • 製品名

      Anti-TBLR1/TBL1XR1 antibody
      TBLR1/TBL1XR1 一次抗体 製品一覧

    • 製品の詳細

      Rabbit polyclonal to TBLR1/TBL1XR1

    • 由来種

      Rabbit

    • 特異性

      Does not cross-react with TBL1.

    • アプリケーション

      適用あり: WBmore details

    • 種交差性

      交差種: Human

    • 免疫原

      Recombinant full length protein corresponding to Human TBLR1/TBL1XR1.

    • 特記事項

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Abpromise保証は、 次のテスト済みアプリケーションにおけるab24550の使用に適用されます

    アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

    アプリケーション Abreviews 特記事項
    WB
    1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 56 kDa).
    特記事項
    WB
    1/2000. Detects a band of approximately 64 kDa (predicted molecular weight: 56 kDa).

    ターゲット情報

    • 機能

      F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.

    • 組織特異性

      Ubiquitous.

    • 配列類似性

      Belongs to the WD repeat EBI family.
      Contains 1 F-box-like domain.
      Contains 1 LisH domain.
      Contains 8 WD repeats.

    • ドメイン

      The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.

    • 翻訳後修飾

      Phosphorylated upon DNA damage, probably by ATM or ATR.

    • 細胞内局在

      Nucleus.
    • Information by UniProt

    • 参照データベース

      • 別名

        • C21 antibody
        • DC42 antibody
        • F box like/WD repeat containing protein TBL1XR1 antibody
        • F-box-like/WD repeat-containing protein TBL1XR1 antibody
        • FLJ12894 antibody
        • IRA1 antibody
        • Nuclear receptor corepressor/HDAC3 complex subunit antibody
        • Nuclear receptor corepressor/HDAC3 complex subunit TBLR1 antibody
        • TBL1 related protein 1 antibody
        • TBL1-related protein 1 antibody
        • TBL1R_HUMAN antibody
        • TBL1XR1 antibody
        • TBLR1 antibody
        • Transducin (beta) like 1 X linked receptor 1 antibody
        • Transducin beta like 1X related protein 1 antibody
        • Transducin beta-like 1X-related protein 1 antibody
        see all

      画像

      参考文献 (13)

      ab24550 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab24550 は 13 報の論文で使用されています。

      • Guo Y  et al. Circ_0035292 knockdown alleviates lipopolysaccharide (LPS)-induced WI-38 cell apoptosis and inflammatory injury. Immun Inflamm Dis 11:e905 (2023). PubMed: 37382271
      • Hall HN  et al. Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. PLoS One 17:e0268149 (2022). PubMed: 36413568
      • Yang H  et al. GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A. iScience 25:104952 (2022). PubMed: 36065190
      • Wu C  et al. Long Noncoding RNA Plasmacytoma Variant Translocation 1 Regulates Cisplatin Resistance via miR-3619-5p/TBL1XR1 Axis in Gastric Cancer. Cancer Biother Radiopharm N/A:N/A (2020). PubMed: 32407172
      • Moretti C  et al. Battle of the Sex Chromosomes: Competition between X and Y Chromosome-Encoded Proteins for Partner Interaction and Chromatin Occupancy Drives Multicopy Gene Expression and Evolution in Muroid Rodents. Mol Biol Evol 37:3453-3468 (2020). PubMed: 32658962
      View all Publications for this product

      レビューと Q&A

      Show All レビュー Q&A
      レビューを送る 質問を送る

      1-3 of 3 Abreviews or Q&A

      ChIP abreview for Anti-TBLR1/TBL1XR1 antibody

       Good
      Abreviews
      abreview image
      Application
      ChIP
      Sample
      Mouse Tissue lysate - whole (Mouse liver)
      Negative control
      IgG
      Specification
      Mouse liver
      Detection step
      Semiquantitative PCR
      Type
      Cross-linking (X-ChIP)
      Duration of cross-linking step: 10 minute(s) and 0 second(s)
      Specification of the cross-linking agent: 37%FORMALDEHYDE
      Positive control
      POL ll
      Read More
      The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

      MR. Natarajan Balasubramaniyan

      Verified customer

      投稿 Sep 04 2013

      Immunoprecipitation abreview for Anti-TBLR1/TBL1XR1 antibody

       Good
      Abreviews
      abreview image
      Application
      Immunoprecipitation
      Sample
      Human Cell lysate - whole cell (lung carcinoma)
      Total protein in input
      500 µg
      Immuno-precipitation step
      Protein G
      Specification
      lung carcinoma
      Read More
      The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

      Abcam user community

      Verified customer

      投稿 Jun 10 2011

      Question

      Please send a testing discount code for testing rat samples in ChIP.

      Read More
      Answer

      This code will give you one free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for ChIP of rat samples and include this code in the “Additional Comments” section so we know the Abreview is for this promotion.

      For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews.

      The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

      Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

      The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com