Anti-Syncollin 抗体 [EPRR13148] (ab178415)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPRR13148] to Syncollin
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
製品の概要
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製品名
Anti-Syncollin antibody [EPRR13148]
Syncollin 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPRR13148] to Syncollin -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: ICC/IF,IHC-P or IP -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Synthetic peptide within Human Syncollin aa 1-100. The exact sequence is proprietary.
Database link: Q0VAF6 -
ポジティブ・コントロール
- Human fetal pancreas, rat pancreas and mouse pancreas lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EPRR13148 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab178415の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/5000. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa).
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特記事項 |
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WB
1/1000 - 1/5000. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa). |
ターゲット情報
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機能
Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. -
翻訳後修飾
Contains intrachain disulfide bonds. -
細胞内局在
Cytoplasmic vesicle > secretory vesicle membrane. Localizes to zymogen granules (By similarity). Associated with lipid rafts in a cholesterol-dependent manner. - Information by UniProt
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参照データベース
- Entrez Gene: 342898 Human
- Entrez Gene: 68416 Mouse
- Entrez Gene: 245917 Rat
- SwissProt: Q0VAF6 Human
- SwissProt: Q8VCK7 Mouse
- SwissProt: O35775 Rat
- Unigene: 124123 Human
- Unigene: 25210 Mouse
see all -
別名
- 0910001K16Rik antibody
- 1810038B08Rik antibody
- FLJ27441 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab178415 は 2 報の論文で使用されています。
- Sudhakar JN et al. Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas. Nat Commun 11:4286 (2020). PubMed: 32855403
- Sendler M et al. Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice. Gastroenterology 154:704-718.e10 (2018). PubMed: 29079517