Anti-Synaptotagmin 抗体 (ab51172)
Key features and details
- Rabbit polyclonal to Synaptotagmin
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Synaptotagmin antibody
Synaptotagmin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Synaptotagmin -
由来種
Rabbit -
アプリケーション
適用あり: ELISA, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
A synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of threonine 202.
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ポジティブ･コントロール
- Human breast carcinoma tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab51172の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA |
1/10000.
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| IHC-P |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
ELISA
1/10000. |
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IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. -
配列類似性
Belongs to the synaptotagmin family.
Contains 2 C2 domains. -
ドメイン
The first C2 domain mediates Ca(2+)-dependent phospholipid binding.
The second C2 domain mediates interaction with Stonin 2. -
細胞内局在
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Synaptic vesicles and chromaffin granules. - Information by UniProt
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参照データベース
- Entrez Gene: 127833 Human
- Entrez Gene: 6857 Human
- Entrez Gene: 6860 Human
- Entrez Gene: 6861 Human
- Entrez Gene: 84258 Human
- Entrez Gene: 20979 Mouse
- Entrez Gene: 20980 Mouse
- Entrez Gene: 24805 Rat
see all -
別名
- HsT1192 antibody
- MYSPC antibody
- P65 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Synaptotagmin antibody (ab51172)Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab51172 at a 1:50 dilution. Left image un-treated; Right image treated with peptide.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab51172 は 1 報の論文で使用されています。
- Legate KR et al. Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type I? in vivo. J Cell Sci 125:5636-46 (2012). PubMed: 22976293